[儿童间性状态的致病形式]。

P Grigorescu Sido, S Imreh, E Opincariu, Z Nicoară, V Oţoiu, C Colesnicov
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引用次数: 0

摘要

本文报告了26例具有间性状态的儿童,属于以下病理类型:1。女性假雌雄同体11例,包括a) I型先天性皮质肾上腺皮质增生(8例)和III型(1例);B)医源性形式(1例),c)皮质肾上腺阳刚性腺瘤(1例);2. 男性假雌雄同体-6例,3例。女性表型性腺发育不良9例,其中a) Turner综合征(6例);b)性腺发育不良45 XO/46 XX(2例)和c) Swyer综合征(1例)。作者强调,在大多数情况下,产前条件特征(染色体或代谢遗传疾病,先天性疾病);他们讨论了诊断标准,治疗的可能性和预防,以及他们的效率,这取决于诊断是建立的时刻。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Pathogenetic forms of intersexuality states in children].

The present paper reports on 26 children with intersexuality states, belonging to the following pathologic forms: 1. female pseudohermaphroditism--11 cases, including a) type I congenital corticoadrenal hyperplasia (8 cases) and type III (1 case); b) iatrogenic form (1 case), and c) corticoadrenal virilizing adenoma (1 case); 2. male pseudohermaphroditism--6 cases, and 3. gonadal dysgenesis of female phenotype--9 cases of which a) Turner syndrome (6 cases); b) gonadal dysgenesis 45 XO/46 XX (2 cases) and c) Swyer syndrome (1 case). The authors emphasize the prenatal conditioned character (chromosomal or metabolic genetic diseases, congenital diseases) in the majority of the cases; they discuss the diagnostic criteria, therapeutical possibilities and prophylaxis as well as their efficiency which depends upon the moment the diagnosis is established.

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