Zixuan Zhang, Wei Li, Jie Liu, Ying Li, Jingfu Qiu, Chaorui Li
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Electrochemical Immunosensor Based on Al-TCPP Nanomaterial Adsorption Aggregation Signal Amplification for the Detection of Dengue Virus NS1 Protein
To detect the dengue virus NS1 protein with high sensitivity, this research suggests an electrochemical immunosensor based on the Al-TCPP adsorption aggregation signal amplification approach. We created a type of metal-organic framework (MOF) material called astrophytum myriostigma, which resembles a cactus plant and has a large specific surface area. In addition, it can produce electrostatic attraction with the amino groups on methylene blue (MB), firmly fix MB on the MOF material, and manage MB reunion after adsorption, which is helpful for electron transmission and amplifies the electrical signal. The cationic dye methylene blue has redox characteristics. It possesses a high electron transfer rate, electrochemical reversibility, and strong biocompatibility. The generated electrochemical immunosensor has good reproducibility and stability, and the relationship between the analyte concentration and electrical signal strength is linear. The suggested immunosensor has a broad detection range from 10 fg/mL to 100 ng/mL with a low detection limit of 9.12 fg/mL under ideal conditions.
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Electrocatalysis is cross-disciplinary in nature, and attracts the interest of chemists, physicists, biochemists, surface and materials scientists, and engineers. Electrocatalysis provides the unique international forum solely dedicated to the exchange of novel ideas in electrocatalysis for academic, government, and industrial researchers. Quick publication of new results, concepts, and inventions made involving Electrocatalysis stimulates scientific discoveries and breakthroughs, promotes the scientific and engineering concepts that are critical to the development of novel electrochemical technologies.
Electrocatalysis publishes original submissions in the form of letters, research papers, review articles, book reviews, and educational papers. Letters are preliminary reports that communicate new and important findings. Regular research papers are complete reports of new results, and their analysis and discussion. Review articles critically and constructively examine development in areas of electrocatalysis that are of broad interest and importance. Educational papers discuss important concepts whose understanding is vital to advances in theoretical and experimental aspects of electrochemical reactions.
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