初生婴儿的高龄产妇和低出生体重

Kezia Adelize Aurelia Junus, Ana Lucia Ekowati, Bertha Soegiarto, Andy Setiawan
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引用次数: 0

摘要

背景:推迟怀孕的妇女人数正在增加。高龄产妇/ AMA(35岁或以上妇女怀孕)增加了并发症的风险,如低出生体重/LBW(高达1.59倍)。本研究的目的是了解初代新生儿中AMA与LBW之间的关系。对象和方法:本描述性和分析性横断面研究包括雅加达Atma Jaya医院的169例初产妇,采用总抽样方法收集2016年2月至2021年9月期间符合纳入标准的新生儿。自变量包括初产妇年龄,因变量包括出生体重。在两个独立的分析中,早产被用作因变量和自变量。对数据特征进行了描述,并使用Fisher精确检验对初生期AMA与LBW、初生期AMA与早产、初生期早产与LBW之间的关系进行了分析。结果:高学历妇女和孕产妇疾病妇女在AMA中所占比例较高。LBW患病率为14.79%。低体重在AMA中的比例较高(OR=2.045;CI 95% 0.513 ~ 8.147),相关性无统计学意义(p=0.253)。产妇年龄与出生体重的相关性不显著(p=0.113)。AMA的早产几率不显著增高(OR=1.139;95%可信区间0.234 ~ 5.538;p = 0.567)。早产与低体重之间的相关性非常显著(OR 49.224;CI 95% 15.470 ~ 156.621;术中,0.001)。结论:年龄≥35岁的初孕妇女患孕产妇疾病的比例较高。尽管统计上不显著,但AMA患LBW的几率更高。早产与低体重高度相关。需要对高危产妇年龄进行进一步研究,以改善妇女和儿童的健康。关键词:高龄产妇,初产妇,低出生体重。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advanced Maternal Age and Low Birth Weight in Primigravid Births
Background: The number of women who delay pregnancy is increasing. Advanced Maternal Age/ AMA (pregnancies in women aged 35 years or older) have increased risks of complications, such as low birth weight/LBW (up to 1.59 times). The aim of this study is to know the association between AMA with LBW in primigravid births. Subjects and Method: This descriptive and analytical, cross sectional research consists of 169 primigravid births in Atma Jaya Hospital Jakarta, collected with a total sampling method for births between February 2016 to September 2021 meeting inclusion criteria. Independent variable included primigravid maternal age and dependent variable included birth weight. Prematurity was used as a dependent variable and an independent variable in two separate analyses. Characteristics of data are described, and analyses were done with the Fisher’s exact test for the associations between primigravid AMA and LBW, , between primigravid AMA and prematurity, and between primigravid prematurity and LBW Spearman’s correlation test was done for the correlation between primigravid maternal age and birth weight. Results: The proportions of women with higher education and maternal diseases are more elevated in AMA. LBW prevalence is 14.79%. The proportion of LBW is higher in AMA (OR=2.045; CI 95% 0.513 to 8.147), with statistically insignificant association (p=0.253). The correlation between maternal age and birth weight is insignificant (p=0.113). AMA has insignificantly higher odds for prematurity (OR=1.139; CI 95% 0.234 to 5.538; p=0.567). The association between prematurity and LBW is highly significant (OR 49.224; CI 95% 15.470 to 156.621; p<0.001). Conclusion: Primigravid women aged ≥35 years have higher proportions of maternal diseases. Despite being statistically insignificant, AMA has higher odds for LBW. Prematurity is highly asso-ciated with LBW. Further research concerning high-risk maternal age needs to be done to improve women’s and children’s health. Keywords: advanced maternal age, primigravida, low birth weight.
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