超声参数结合临床病理参数预测三阴性乳腺癌腋窝淋巴结转移的价值

IF 0.5 4区 医学 Q4 OBSTETRICS & GYNECOLOGY
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引用次数: 0

摘要

回顾性分析119例三阴性乳腺癌(TNBC)患者的临床资料,对比发现腋窝淋巴结转移者与未发生腋窝淋巴结转移者在年龄、病变组织学分级、Ki-67表达、病变形态、内部血流量、以及腋窝淋巴结的超声表现对病灶在病灶象限内分布的超声表现(p <0.05)。多因素回归分析提示,年龄、组织学分级、病变象限、腋窝淋巴结超声表现均是影响TNBC患者腋窝淋巴结转移的相关因素,利用多因素回归分析结果构建TNBC患者腋窝淋巴结转移预测模型。ROC曲线分析结果显示,logistic回归模型预测TNBC患者腋窝淋巴结转移的AUC为0.761,敏感性为0.824,特异性为0.714。提示超声结合病理参数对TNBC患者腋窝淋巴结转移的临床判断有一定价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The value of ultrasonic parameters combined with clinicopathological parameters in predicting axillary lymph node metastasis in triple-negative breast cancer
The clinical data of 119 patients with triple-negative breast cancer (TNBC) were retrospectively analyzed, and comparisons revealed that the differences between those who developed axillary lymph node metastasis and those who did not were statistically significant when comparing the age, histological grading of the lesions, expression of Ki-67, and information about the morphology of the lesions, internal blood flow, and the ultrasonographic manifestations of axillary lymph nodes on ultrasonography of the distribution of the lesions in the lesions’ quadrants (p < 0.05). Multifactorial regression analysis suggested that age, histological grade, lesion quadrant, and axillary lymph node ultrasound performance were all relevant factors affecting axillary lymph node metastasis in TNBC patients; the predictive model of axillary lymph node metastasis in TNBC was constructed with the results of multifactorial regression analysis, and the results of the ROC curve analysis showed that the logistic regression model had an AUC of 0.761 and the sensitivity and specificity were 0.824 and 0.714, respectively, for predicting the metastasis of the axillary lymph nodes in TNBC patients. This suggests that ultrasound combined with pathological parameters has some value in helping clinical judgment of axillary lymph node metastasis in TNBC patients.
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来源期刊
自引率
25.00%
发文量
58
审稿时长
1 months
期刊介绍: EJGO is dedicated to publishing editorial articles in the Distinguished Expert Series and original research papers, case reports, letters to the Editor, book reviews, and newsletters. The Journal was founded in 1980 the second gynaecologic oncology hyperspecialization Journal in the world. Its aim is the diffusion of scientific, clinical and practical progress, and knowledge in female neoplastic diseases in an interdisciplinary approach among gynaecologists, oncologists, radiotherapists, surgeons, chemotherapists, pathologists, epidemiologists, and so on.
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