{"title":"Na+离子在血管紧张素II刺激大鼠获得性主动回避中的意义。","authors":"J Boguszewicz, J J Braszko","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Angiotensin II (1 microgram) dissolved in water and given intracerebroventricularly on day 1, 15 min before the first learning session, enhanced rate of learning of active avoidance in rats over the next 7 days. However, the peptide, dissolved in 0.25 M NaCl, and given at the same dose and route, stimulated learning significantly more than that dissolved in water. A possible involvement of Na+ ions in facilitating learning action of A II is discussed.</p>","PeriodicalId":7158,"journal":{"name":"Acta physiologica Polonica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1989-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The significance of Na+ ions in angiotensin II stimulation of acquisition of active avoidance in rats.\",\"authors\":\"J Boguszewicz, J J Braszko\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Angiotensin II (1 microgram) dissolved in water and given intracerebroventricularly on day 1, 15 min before the first learning session, enhanced rate of learning of active avoidance in rats over the next 7 days. However, the peptide, dissolved in 0.25 M NaCl, and given at the same dose and route, stimulated learning significantly more than that dissolved in water. A possible involvement of Na+ ions in facilitating learning action of A II is discussed.</p>\",\"PeriodicalId\":7158,\"journal\":{\"name\":\"Acta physiologica Polonica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta physiologica Polonica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta physiologica Polonica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
血管紧张素II(1微克)溶解于水，在第1天第一次学习前15分钟脑室内注射，在接下来的7天内提高了大鼠主动回避的学习率。然而，在相同剂量和途径下，将肽溶解在0.25 M NaCl中，对学习的刺激明显大于溶解在水中的肽。讨论了Na+离子参与促进aii学习的可能性。
The significance of Na+ ions in angiotensin II stimulation of acquisition of active avoidance in rats.
Angiotensin II (1 microgram) dissolved in water and given intracerebroventricularly on day 1, 15 min before the first learning session, enhanced rate of learning of active avoidance in rats over the next 7 days. However, the peptide, dissolved in 0.25 M NaCl, and given at the same dose and route, stimulated learning significantly more than that dissolved in water. A possible involvement of Na+ ions in facilitating learning action of A II is discussed.
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