[来自ribebe o Preto地区(s o Paulo)人群样本中的2型糖尿病患者]。

M C Foss, G M Paccola, N V de Souza, N Iazigi
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引用次数: 0

摘要

为了描述长期糖尿病并发症(大血管病变、视网膜病变、肾病和神经病变)的患病率及其与糖尿病代谢控制程度和病程的可能关系,我们研究了巴西546名非胰岛素依赖型糖尿病患者的医院样本。该小组接受了标准化的评估方案,包括患者及其疾病的临床特征、当前治疗、代谢控制程度和糖尿病并发症的存在。研究样本为成人(25 - 84岁),平均糖尿病病程为8.0 +/- 6.8年。肥胖发生率为72.6%,亲属中有糖尿病患者232例(43.3%)。92例(18.4%)患者仅接受饮食治疗,170例(32.6%)患者同时使用口服降糖药,226例(43.7%)患者使用NPH胰岛素治疗(81.4%为单次每日剂量)。根据该组患者的年平均空腹血糖(187 +/- 68mg/dl)、尿糖(9.6 +/- 16.7g/天)和糖化血红蛋白(12.2 +/- 3.3%)水平,可以对患者进行分类:a)代谢控制良好(106分)。= 19.4%);B)常规控制。= 48.4%)和c)代谢控制不良(176分)。= 32.2%)。微血管及神经病变的患病率为:视网膜病变为29.1%,肾病为11.3%,神经病变为50.9%。观察到的并发症发生率的增加是渐进式的,根据糖尿病的持续时间。在糖尿病病程的所有时间间隔中,神经病变是最常见的并发症。代谢控制不良组的并发症发生率高于代谢控制良好组。(摘要删节250字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Type 2 diabetic patients in a population sample from Ribeirão Preto area (São Paulo)].

To characterize the prevalence of long term diabetic complications (macroangiopathy, retinopathy, nephropathy and neuropathy) and their possible relation to the degree of metabolic control and duration of diabetes, we studied a hospital-based brazilian population sample of 546 non-insulin dependent diabetic patients. The group was subjected to a standardized evaluation protocol, including clinical characterization of the patients and their disease, current therapy, degree of metabolic control and presence of diabetic complications. The studied sample is of adult age range (25 to 84 years), with mean duration of diabetes of 8.0 +/- 6.8 years. Obesity was observed in 72.6% of the group and 232 patients (43.3%) had diabetics among their relatives. 92 (18.4%) patients have been treated with diet only, whereas 170 (32.6%) also used oral hypoglycemic agents, and 226 (43.7%) were using NPH insulin therapy (81.4% with single daily dose). The mean annual levels of fasting blood glucose (187 +/- 68mg/dl), urine glucose (9.6 +/- 16.7g/day) and glycosylated hemoglobin (12.2 +/- 3.3%) of the group, permitted a classification of the patients in: a) good metabolic control (106 pat. = 19.4%); b) regular control (264 pat. = 48.4%) and c) poor metabolic control (176 pat. = 32.2%). The prevalences of microvascular and neuropathic complications was: retinopathy = 29.1%, nephropathy = 11.3% and neuropathy = 50.9%. The observed increase in the prevalence of the complications was progressive according to the duration of the diabetes. In all time intervals of duration of diabetes, neuropathy was the most frequently observed complication. The prevalence of complications was always higher in the poorly controlled group compared to the patients in good metabolic control.(ABSTRACT TRUNCATED AT 250 WORDS)

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