LGI1和caspr2相关的Morvan综合征——儿科病例的诊断挑战

Q4 Medicine
Elena Catalina Petrov, Diana Anamaria Epure, Oana Aurelia Vladacenco, Daniela Dorina Vasile, Maria Lupu, Eugenia Roza, Raluca Ioana Teleanu
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引用次数: 0

摘要

Morvan综合征是一种罕见的免疫介导的病理涉及中枢,外周和自主神经系统。虽然它在成人中被描述为一种副肿瘤综合征,但在儿科患者中很少见到。在本报告中,我们报告了一名15岁的男性患者,他经历了失眠,周围神经亢奋和自主神经体征,高度提示Morvan综合征,但也容易诊断困境。诊断被证实存在抗电压门控钾通道(VGKC)的抗体。这篇文章的目的是强调一个罕见的综合征,诊断陷阱和治疗方案的儿科患者独特的临床图片。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
LGI1 and CASPR2-related Morvan syndrome - diagnostic challenges in a pediatric case
Morvan syndrome is a rare immune-mediated pathology involving the central, peripheral and autonomic nervous systems. Although it was described in adults, mostly as a paraneoplastic syndrome, it is rarely seen in pediatric patients. In this report, we present the case of a 15-year-old male patient who experienced insomnia, peripheral nerve hyperexcitability and autonomic signs, highly suggestive for Morvan syndrome, but prone to diagnostic dilemmas as well. The diagnosis was confirmed by the presence of antibodies against voltage-gated potassium channels (VGKC). This article aims to highlight the unique clinical picture of a rare syndrome, diagnostic pitfalls and treatment options in pediatric patients.
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CiteScore
0.10
自引率
0.00%
发文量
15
审稿时长
4 weeks
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