内生新杆菌BRMEA1T耐热适应性的基因组研究

Q4 Agricultural and Biological Sciences

Research in Plant Disease Pub Date : 2023-09-30 DOI:10.5423/rpd.2023.29.3.321

Lingmin Jiang, Ho Le Han, Yuxin Peng, Doeun Jeon, Donghyun Cho, Cha Young Kim, Jiyoung Lee

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引用次数: 0

摘要

内生新杆菌brme1 /sup>，从药用植物卷柏(Selaginella involved )中分离出来，因其耐高温可在50°C下生长而闻名。为了探索其耐热反应的遗传基础及其产生有价值天然化合物的潜力，研究了2个耐高温菌株和4个中温菌株使用生物信息学软件平台进行分析。利用RAST SEED和OrthVenn2对整个基因组进行了注释，重点鉴定了潜在的耐热性相关基因。& lt; i> N。endophyticusBRMEA1 T与其他中温菌属成员相比，它被发现具有更多的应激反应基因，并且是唯一具有合成渗透调节的质周葡聚糖基因的菌株。这项研究揭示了N的潜在价值。endophyticusBRMEA1T，通过全基因组测序和对比分析，揭示了该细菌耐热的机理及其产生的次生代谢物的应用。

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Genome-Based Insights into the Thermotolerant Adaptations of Neobacillus endophyticus BRMEA1T

The bacterium Neobacillus endophyticus BRMEA1^T, isolated from the medicinal plant Selaginella involvens, known as its thermotolerant can grow at 50°C. To explore the genetic basis for its heat tolerance response and its potential for producing valuable natural compounds, the genomes of two thermotolerant and four mesophilic strains in the genus Neobacillus were analyzed using a bioinformatic software platform. The whole genome was annotated using RAST SEED and OrthVenn2, with a focus on identifying potential heattolerance- related genes. N. endophyticus BRMEA1^T was found to possess more stress response genes compared to other mesophilic members of the genus, and it was the only strain that had genes for the synthesis of osmoregulated periplasmic glucans. This study sheds light on the potential value of N. endophyticus BRMEA1^T, as it reveals the mechanism of heat resistance and the application of secondary metabolites produced by this bacterium through whole-genome sequencing and comparative analysis.

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来源期刊

Research in Plant Disease Agricultural and Biological Sciences-Agronomy and Crop Science

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

18 weeks