一些分枝杆菌菌株在含auramine的7H12 Middlebrook液体培养基中生长。

Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia Pub Date : 1989-04-01

S Botis, P P Koemoth, J M Correa de Brito, M Brock

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摘要

研究了auramine在7H12 Middlebrook液体培养基中对部分分枝杆菌菌株生长的影响，以及auramine与小牛胸腺DNA的相互作用。由此可见，金胺对结核分枝杆菌或MOTT杆菌的抑制作用是金胺与霉菌酸的相互作用和染料与分枝杆菌DNA的相互作用的双重机制。

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Growth of some mycobacterial strains in 7H12 Middlebrook liquid medium in the presence of auramine.

The action of auramine on the growth of some mycobacterial strains in 7H12 Middlebrook liquid medium as well as the interaction between auramine and calf thymus DNA were investigated. It was concluded that the inhibitory effect of auramine on the growth of some mycobacterial strains belonging to the TB complex or MOTT bacilli is the result of a double mechanism: interaction of auramine with mycolic acid and interaction between the dye and the mycobacterial DNA.

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Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia

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