The Role of Quercetin, Curcumin, Eugenol, and Andrographolide in COVID-19 Treatment: A Review of Their Mechanisms of Action and Clinical Efficacy

The world has recently experienced the covid diseases. It became the global worry with no remedy initially. Later, different antiviral medications in the form of injections and nasal sprays began to be employed. Many studies have been conducted to determine the antiviral effects of phytochemical substances. The corona virus's spike protein interacts with the ACE2 receptors on the alveoli's surface to enter the cell. After that, the polyprotein is transformed into an effector protein by a number of protease enzymes, including Mpro, 3CLpro, and PLpro. There are several ways to stop the contagious illness from spreading, nevertheless we must somehow halt these behaviours from occurring. Many phytochemical compounds with antiviral activity can be found in nature. The potential antiviral effects of Quercetin, Curcumin, eugenol, and andrographolide against SARS-CoV- 2 infection were highlighted in this review.