人类接种部分牛结核模型的研究

IF 0.5 Q4 COMPUTER SCIENCE, INFORMATION SYSTEMS
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引用次数: 0

摘要

牛结核病是一种细菌和人畜共患疾病,可通过吸入气溶胶、饮用未经巴氏消毒的牛奶或食用生肉而感染。本研究使用带有卡普托传感和人类疫苗接种室的分数阶模型调查了牛结核病在人类和动物种群中的传播演变。利用Volterratype Lyapunov函数、LaSalle不变性原理和Routh-Hurwitz准则构造阈值R0来识别病态状态,并提供保证平衡点局部和全局渐近稳定的条件。为了确定控制bTB动态的变量,我们进行了敏感性研究。分析表明,影响结核传播的因素包括环境污染率、动物间结核传播率以及人通过受感染动物和环境感染结核的比率。然而,随着疫苗接种率的上升和受污染环境产品(肉类和乳制品)消费量的下降,这种疾病在人类中变得不那么常见了。对于结核分枝杆菌的管理,建议实施教育举措,监测环境,治疗受影响的个体,进行免疫接种,并限制受污染的动物。数值实验证明了所得理论结果的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A study of fractional bovine tuberculosis model with vaccination on human population
A bacterial and zoonotic disease called bovine tuberculosis (bTB) can be contracted by breathing in aerosols, consuming unpasteurized milk, or eating raw meat. The evolution of bovine tuberculosis transmission in both human and animal populations is investigated in this research using a fractional order model with caputo sensing and a compartment for human vaccination. The threshold quantity R0 was also constructed using Volterratype Lyapunov functions, LaSalle’s invariance principle, and the Routh-Hurwitz criterion to identify the sick state and provide conditions that guarantee the local and global asymptotic stability of the equilibria. In order to determine the variables that control the dynamics of bTB, we performed a sensitivity study. The analysis indicates that factors influencing the spread of bTB include the rate of environmental contamination, the rate of bTB transmission from animal to animal, and the rate at which bTB is contracted by people from infected animals and the environment. However, the disease becomes less common in humans as vaccination rates rise and consumption of the contaminated environment’s products (meat and dairy products) declines. For the management of bTB, it is recommended to implement educational initiatives, monitor the environment, treat affected individuals, administer immunizations, and confine contaminated animals. Numerical experiments are used to show how useful the found theoretical results are.
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来源期刊
Communications in Mathematical Biology and Neuroscience
Communications in Mathematical Biology and Neuroscience COMPUTER SCIENCE, INFORMATION SYSTEMS-
CiteScore
2.10
自引率
15.40%
发文量
80
期刊介绍: Communications in Mathematical Biology and Neuroscience (CMBN) is a peer-reviewed open access international journal, which is aimed to provide a publication forum for important research in all aspects of mathematical biology and neuroscience. This journal will accept high quality articles containing original research results and survey articles of exceptional merit.
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