使用分布式参数系统的免疫过程多物理场建模

IF 0.5 4区数学 Q4 MATHEMATICS, APPLIED

Russian Journal of Numerical Analysis and Mathematical Modelling Pub Date : 2023-10-01 DOI:10.1515/rnam-2023-0021

Gennady A. Bocharov, Dmitry S. Grebennikov, Rostislav S. Savinkov

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引用次数: 0

摘要

免疫系统是一个由细胞组成的复杂的分布式系统，它们在机体内循环、交流和周转，以响应抗原干扰。我们讨论了模拟人类和实验动物免疫系统功能的新方法，重点关注其“复杂性”。本文回顾了新兴的数学和计算机模型，以描述免疫系统的多样性、细胞/细胞因子网络通信结构、等级调节和免疫库的进化动态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Multiphysics modelling of immune processes using distributed parameter systems

Abstract The immune system is a complex distributed system consisting of cells, which circulate through the body, communicate and turnover in response to antigenic perturbations. We discuss new approaches to modelling the functioning of the immune system of humans and experimental animals with a focus on its ‘complexity’. Emerging mathematical and computer models are reviewed to describe the immune system diversity, the cell/cytokine network communication structures, hierarchical regulation, and evolutionary dynamics of immune repertoires.

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来源期刊

Russian Journal of Numerical Analysis and Mathematical Modelling 数学-工程：综合

CiteScore

1.40

自引率

16.70%

发文量

审稿时长

>12 weeks

期刊介绍： The Russian Journal of Numerical Analysis and Mathematical Modelling, published bimonthly, provides English translations of selected new original Russian papers on the theoretical aspects of numerical analysis and the application of mathematical methods to simulation and modelling. The editorial board, consisting of the most prominent Russian scientists in numerical analysis and mathematical modelling, selects papers on the basis of their high scientific standard, innovative approach and topical interest. Topics: -numerical analysis- numerical linear algebra- finite element methods for PDEs- iterative methods- Monte-Carlo methods- mathematical modelling and numerical simulation in geophysical hydrodynamics, immunology and medicine, fluid mechanics and electrodynamics, geosciences.