恢复生活质量:评估冠状病毒病2019相关鼻-眶毛霉菌病患者游离皮瓣重建的影响

IF 0.7 Q4 SURGERY
Neeraj Rao, Anand Agrawal, Akshay Kapoor, Vishal Mago, Madhubari Vathulya, Debarati Chattopadhyay
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引用次数: 0

摘要

背景在印度,2021年5月5日至7月期间,2019冠状病毒病(COVID-19)感染患者或COVID-19康复患者中报告了41512例和3554例因毛霉菌病死亡。与covid -19相关的鼻-眶粘膜真菌病(CAROM)与可影响口腔健康、视力、身体和情绪功能的不良反应有关。CAROM根治性清创和抗真菌治疗后,应采用重建手术恢复功能和美观;然而,关于其对这些患者生活质量(QOL)的潜在影响的临床数据有限。目的评价游离皮瓣重建CAROM患者的生活质量。材料与方法本研究分析了19例在三级保健中心进行上颌切除和/或眶内清除缺损重建的CAROM患者。所有患者均无任何残留疾病,经患处组织活检证实。术前1周和术后4 ~ 6个月采用欧洲癌症研究与治疗组织头颈部生活质量问卷(EORTC QLQ-HN43)问卷模块评估患者的生活质量。结果19个参数中有10个有统计学意义的改善(p <0.05),包括口腔疼痛、张嘴困难、说话困难、吞咽困难、体重减轻、口干和唾液粘稠、身体形象、害怕进步、社交接触和社交性饮食。结论EORTC QLQ-HN43问卷模块对游离皮瓣重建CAROM患者的功能和心理状况有显著改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Restoring Quality of Life: Assessing the Impact of Free Flap Reconstruction in Coronavirus Disease 2019-Associated Rhino-Orbital Mucormycosis Patients
Abstract Background In India, between May 5 and July 2021, 41,512 cases and 3,554 deaths due to mucormycosis were reported in coronavirus disease 2019 (COVID-19)-infected patients or COVID-19-recovered patients. COVID-19-associated rhino-orbital mucormycosis (CAROM) has been associated with adverse effects that can affect oral health, vision, and physical as well as emotional functioning. After the radical debridement of CAROM and antifungal therapy, reconstructive surgery should be employed to restore function and aesthetics; however, limited clinical data exist on its potential effect on the quality of life (QOL) of these patients. Objective Our objective was to assess the QOL among CAROM patients reconstructed with free flap surgery. Materials and Methods This analysis studied 19 patients of CAROM who had maxillectomy and/or orbital exenteration defects reconstructed with free flaps at a tertiary care center. All these patients were free from any residual disease, as confirmed by tissue biopsy taken from the affected area. The QoL of these patients was assessed 1 week preoperatively and 4 to 6 months postoperatively using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module (EORTC QLQ-HN43) questionnaire module. Results There was a statistically significant improvement in 10 out of the total 19 parameters (p < 0.05) which include pain in the mouth, problems opening mouth, speech, swallowing, weight loss, dry mouth and sticky saliva, body image, fear of progression, social contact, and social eating. Conclusion The EORTC QLQ-HN43 questionnaire module presented a statistically significant improvement in the functional as well as psychological status of the CAROM patients undergoing reconstruction by free flap surgery.
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来源期刊
CiteScore
0.80
自引率
12.50%
发文量
64
审稿时长
27 weeks
期刊介绍: Indian Journal of Plastic Surgery (ISSN : 0970-0358) is biannual publication of the Association of Plastic Surgeons of India. Bibliographic listings: The journal is indexed with Bioline International, Caspur, DOAJ, EBSCO Publishing’s Electronic Databases, Expanded Academic ASAP, Genamics JournalSeek, Google Scholar, Health & Wellness Research Center, Health Reference Center Academic, Hinari, Index Copernicus, IndMed, OpenJGate, PubMed, Pubmed Central, Scimago Journal Ranking, SCOLOAR, SCOPUS, SIIC databases, SNEMB, Ulrich’s International Periodical Directory
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