Rex Wan-Hin Hui, Nadir Abbas, Philip Dunne, Dhiraj Tripathi
{"title":"预测和优化肝硬化患者的非肝手术风险:来自#FGDebate的见解","authors":"Rex Wan-Hin Hui, Nadir Abbas, Philip Dunne, Dhiraj Tripathi","doi":"10.1136/flgastro-2023-102510","DOIUrl":null,"url":null,"abstract":"PROGNOSTIC SCORES The debate kickedoff with a case presentation, followed by discussion on prognostic scores for estimating surgical risks. Among online participants, 53.2% chose the ChildTurcottePugh (CTP) or Model for Endstage Liver Disease (MELD) scores for risk prediction. Other scores chosen included the VOCALPenn Score (26.2%), Mayo Surgical Score (16.3%) and Hepatic Venous Pressure Gradient (HVPG) (4.3%). Most respondents chose CTP or MELD as these were familiar and triedandtested. However, neither CTP or MELD truly assesses the presence or severity of portal hypertension—the sequelae of liver disease most relevant in determining operative risks. The American Society of Anesthesiologists (ASA) classification was also proposed, given its long history in surgical risk stratification. The VOCALPenn and Mayo Surgical scores are designed for surgical risk assessment in cirrhosis. VOCALPenn is the only score to account for surgical factors, whereas the Mayo Surgical score incorporated the ASA classification. These scores were developed using retrospective data, and portal hypertension assessment may be more direct in predicting postoperative decompensation. Preoperative HVPG accurately assesses portal hypertension and has been studied for adverse outcome prediction. However, given the invasive and impractical nature of HVPG, alternatives such as liver/spleen stiffness and endoscopic ultrasoundguided portal pressure assessment were discussed. Participants agreed that these modalities have not been tested in preoperative settings and require validation. SERVICE PROVISION Discussions progressed to service provision and which clinicians should manage patients with cirrhosis undergoing nonhepatic surgery. Considering the potential role of HVPG, tertiary centres with interventional radiology expertise are required. The importance of multidisciplinary care was highlighted, as good communication between hepatologists, anaesthesiologists and surgeons would be critical. The role of allied health colleagues (ie, physiotherapists and dietitians) to provide personalised preoperative, perioperative and postoperative care was also raised.","PeriodicalId":46937,"journal":{"name":"Frontline Gastroenterology","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Predicting and optimising risks for non-hepatic surgery in patients with cirrhosis: insights from the #FGDebate\",\"authors\":\"Rex Wan-Hin Hui, Nadir Abbas, Philip Dunne, Dhiraj Tripathi\",\"doi\":\"10.1136/flgastro-2023-102510\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"PROGNOSTIC SCORES The debate kickedoff with a case presentation, followed by discussion on prognostic scores for estimating surgical risks. Among online participants, 53.2% chose the ChildTurcottePugh (CTP) or Model for Endstage Liver Disease (MELD) scores for risk prediction. Other scores chosen included the VOCALPenn Score (26.2%), Mayo Surgical Score (16.3%) and Hepatic Venous Pressure Gradient (HVPG) (4.3%). Most respondents chose CTP or MELD as these were familiar and triedandtested. However, neither CTP or MELD truly assesses the presence or severity of portal hypertension—the sequelae of liver disease most relevant in determining operative risks. The American Society of Anesthesiologists (ASA) classification was also proposed, given its long history in surgical risk stratification. The VOCALPenn and Mayo Surgical scores are designed for surgical risk assessment in cirrhosis. VOCALPenn is the only score to account for surgical factors, whereas the Mayo Surgical score incorporated the ASA classification. These scores were developed using retrospective data, and portal hypertension assessment may be more direct in predicting postoperative decompensation. Preoperative HVPG accurately assesses portal hypertension and has been studied for adverse outcome prediction. However, given the invasive and impractical nature of HVPG, alternatives such as liver/spleen stiffness and endoscopic ultrasoundguided portal pressure assessment were discussed. Participants agreed that these modalities have not been tested in preoperative settings and require validation. SERVICE PROVISION Discussions progressed to service provision and which clinicians should manage patients with cirrhosis undergoing nonhepatic surgery. Considering the potential role of HVPG, tertiary centres with interventional radiology expertise are required. The importance of multidisciplinary care was highlighted, as good communication between hepatologists, anaesthesiologists and surgeons would be critical. The role of allied health colleagues (ie, physiotherapists and dietitians) to provide personalised preoperative, perioperative and postoperative care was also raised.\",\"PeriodicalId\":46937,\"journal\":{\"name\":\"Frontline Gastroenterology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2023-09-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontline Gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/flgastro-2023-102510\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontline Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/flgastro-2023-102510","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Predicting and optimising risks for non-hepatic surgery in patients with cirrhosis: insights from the #FGDebate
PROGNOSTIC SCORES The debate kickedoff with a case presentation, followed by discussion on prognostic scores for estimating surgical risks. Among online participants, 53.2% chose the ChildTurcottePugh (CTP) or Model for Endstage Liver Disease (MELD) scores for risk prediction. Other scores chosen included the VOCALPenn Score (26.2%), Mayo Surgical Score (16.3%) and Hepatic Venous Pressure Gradient (HVPG) (4.3%). Most respondents chose CTP or MELD as these were familiar and triedandtested. However, neither CTP or MELD truly assesses the presence or severity of portal hypertension—the sequelae of liver disease most relevant in determining operative risks. The American Society of Anesthesiologists (ASA) classification was also proposed, given its long history in surgical risk stratification. The VOCALPenn and Mayo Surgical scores are designed for surgical risk assessment in cirrhosis. VOCALPenn is the only score to account for surgical factors, whereas the Mayo Surgical score incorporated the ASA classification. These scores were developed using retrospective data, and portal hypertension assessment may be more direct in predicting postoperative decompensation. Preoperative HVPG accurately assesses portal hypertension and has been studied for adverse outcome prediction. However, given the invasive and impractical nature of HVPG, alternatives such as liver/spleen stiffness and endoscopic ultrasoundguided portal pressure assessment were discussed. Participants agreed that these modalities have not been tested in preoperative settings and require validation. SERVICE PROVISION Discussions progressed to service provision and which clinicians should manage patients with cirrhosis undergoing nonhepatic surgery. Considering the potential role of HVPG, tertiary centres with interventional radiology expertise are required. The importance of multidisciplinary care was highlighted, as good communication between hepatologists, anaesthesiologists and surgeons would be critical. The role of allied health colleagues (ie, physiotherapists and dietitians) to provide personalised preoperative, perioperative and postoperative care was also raised.
期刊介绍:
Frontline Gastroenterology publishes articles that accelerate adoption of innovative and best practice in the fields of gastroenterology and hepatology. Frontline Gastroenterology is especially interested in articles on multidisciplinary research and care, focusing on both retrospective assessments of novel models of care as well as putative future directions of best practice. Specifically Frontline Gastroenterology publishes articles in the domains of clinical quality, patient experience, service provision and medical education.