一种基于ROS-SVM的多靶点药物类型检测模型

Q3 Decision Sciences
Nur Ghaniaviyanto Ramadhan, Azka Khoirunnisa, Kurnianingsih Kurnianingsih, Takako Hashimoto
{"title":"一种基于ROS-SVM的多靶点药物类型检测模型","authors":"Nur Ghaniaviyanto Ramadhan, Azka Khoirunnisa, Kurnianingsih Kurnianingsih, Takako Hashimoto","doi":"10.30630/joiv.7.3.1171","DOIUrl":null,"url":null,"abstract":"Misleading in determining the decision to use the target drug will be fatal, even to death. This study examines five pharmacological targets designated as types A, B, C, X, and Y. Early detection of misleading drug targeting will reduce the risk of death. This study aims to develop hybrid random oversampling techniques (ROS) and support vector machine (SVM) methods. The use of the oversampling technique in this study aims to balance classes in the dataset; due to the data collection in each class, there is a relatively large gap. This study applies five schemes to see which combination of models produces the highest accuracy. This study also uses five types of SVM kernels, linear, polynomial, gaussian, RBF, and sigmoid, combined with the ROS oversampling technique. Our proposed model combines the ROS oversampling technique with a linear SVM kernel. We evaluated the proposed model and resulted in an accuracy of 97% and compared it with several experiments, including the ROS technique with a sigmoid kernel which only resulted in 50% accuracy. It can be seen from the results obtained that the linear kernel is very adaptive to data types in the form of numeric and nominal compared to other kernels. The method proposed in this study can be applied to other medical problems. Future research can be carried out using a combination of other sampling techniques with deep learning-based methods on this issue.","PeriodicalId":32468,"journal":{"name":"JOIV International Journal on Informatics Visualization","volume":"78 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Hybrid ROS-SVM Model for Detecting Target Multiple Drug Types\",\"authors\":\"Nur Ghaniaviyanto Ramadhan, Azka Khoirunnisa, Kurnianingsih Kurnianingsih, Takako Hashimoto\",\"doi\":\"10.30630/joiv.7.3.1171\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Misleading in determining the decision to use the target drug will be fatal, even to death. This study examines five pharmacological targets designated as types A, B, C, X, and Y. Early detection of misleading drug targeting will reduce the risk of death. This study aims to develop hybrid random oversampling techniques (ROS) and support vector machine (SVM) methods. The use of the oversampling technique in this study aims to balance classes in the dataset; due to the data collection in each class, there is a relatively large gap. This study applies five schemes to see which combination of models produces the highest accuracy. This study also uses five types of SVM kernels, linear, polynomial, gaussian, RBF, and sigmoid, combined with the ROS oversampling technique. Our proposed model combines the ROS oversampling technique with a linear SVM kernel. We evaluated the proposed model and resulted in an accuracy of 97% and compared it with several experiments, including the ROS technique with a sigmoid kernel which only resulted in 50% accuracy. It can be seen from the results obtained that the linear kernel is very adaptive to data types in the form of numeric and nominal compared to other kernels. The method proposed in this study can be applied to other medical problems. Future research can be carried out using a combination of other sampling techniques with deep learning-based methods on this issue.\",\"PeriodicalId\":32468,\"journal\":{\"name\":\"JOIV International Journal on Informatics Visualization\",\"volume\":\"78 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JOIV International Journal on Informatics Visualization\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30630/joiv.7.3.1171\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Decision Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JOIV International Journal on Informatics Visualization","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30630/joiv.7.3.1171","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Decision Sciences","Score":null,"Total":0}
引用次数: 0

摘要

错误地决定使用目标药物将是致命的,甚至是死亡。本研究考察了A、B、C、X和y五种类型的药物靶点。早期发现误导的药物靶点将降低死亡风险。本研究旨在发展混合随机过采样技术(ROS)和支持向量机(SVM)方法。在本研究中使用过采样技术的目的是平衡数据集中的类别;由于每个班级的数据收集,存在比较大的差距。这项研究应用了五种方案,看看哪种模型组合能产生最高的精度。本研究还使用了线性、多项式、高斯、RBF和sigmoid五种SVM核,并结合ROS过采样技术。我们提出的模型结合了ROS过采样技术和线性支持向量机核。我们对所提出的模型进行了评估,得出了97%的准确率,并将其与几个实验进行了比较,包括具有s型核的ROS技术,其准确率仅为50%。从得到的结果可以看出,与其他核相比,线性核对数值和标称形式的数据类型具有很强的适应性。本研究提出的方法可以应用于其他医学问题。未来的研究可以将其他采样技术与基于深度学习的方法结合起来进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Hybrid ROS-SVM Model for Detecting Target Multiple Drug Types
Misleading in determining the decision to use the target drug will be fatal, even to death. This study examines five pharmacological targets designated as types A, B, C, X, and Y. Early detection of misleading drug targeting will reduce the risk of death. This study aims to develop hybrid random oversampling techniques (ROS) and support vector machine (SVM) methods. The use of the oversampling technique in this study aims to balance classes in the dataset; due to the data collection in each class, there is a relatively large gap. This study applies five schemes to see which combination of models produces the highest accuracy. This study also uses five types of SVM kernels, linear, polynomial, gaussian, RBF, and sigmoid, combined with the ROS oversampling technique. Our proposed model combines the ROS oversampling technique with a linear SVM kernel. We evaluated the proposed model and resulted in an accuracy of 97% and compared it with several experiments, including the ROS technique with a sigmoid kernel which only resulted in 50% accuracy. It can be seen from the results obtained that the linear kernel is very adaptive to data types in the form of numeric and nominal compared to other kernels. The method proposed in this study can be applied to other medical problems. Future research can be carried out using a combination of other sampling techniques with deep learning-based methods on this issue.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
JOIV International Journal on Informatics Visualization
JOIV International Journal on Informatics Visualization Decision Sciences-Information Systems and Management
CiteScore
1.40
自引率
0.00%
发文量
100
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信