新型冠状病毒肺炎对急诊普外科手术后疗效的影响

Bora Barut, Yusuf Murat Bag
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摘要

目的:在2019冠状病毒病(COVID-19)大流行期间,许多选择性手术被推迟,而紧急手术不可避免地继续进行。众所周知,与选择性手术相比,紧急普通外科手术的结果更差。此外,COVID-19本身可能会导致呼吸窘迫和多器官功能障碍,从而恶化手术效果。我们的目的是在本研究中提供COVID-19大流行期间因创伤和急诊普外科疾病接受手术的患者数据以及COVID-19对手术结果的影响。方法:纳入2020年3月至2021年1月期间因创伤或急诊接受手术的235例患者。根据COVID-19状态分为阳性(n=16)和阴性(n=219)两组。对两组的人口统计学、临床、实验室和围手术期数据进行分析和比较。结果:患者中位年龄51岁(18 ~ 97岁),男性144例(61.2%)。最常见的诊断是急性阑尾炎(n= 121, 51.5%),其次是肠梗阻。亚组比较显示,COVID-19(+)组合并症患者较多,c反应蛋白值较高,差异均有统计学意义(p= 0.049, p= 0.001)。COVID-19(+)组开放手术次数明显增加(p= 0.037)。COVID-19(+)组术后严重并发症和死亡率较高,但差异无统计学意义。COVID-19患者住院时间明显延长(p= 0.007)。结论:在急诊手术中发现COVID-19阳性对术后手术效果有负面影响。目前尚不清楚这种消极情绪是由于COVID-19疾病本身还是由于COVID-19患者的较差特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of COVID-19 on postoperative outcomes of emergency general surgery operations
Aims: During the pandemic due to Coronavirus disease 2019 (COVID-19) many elective operations were postponed, while emergency surgical operations inevitably continued. Emergency general surgery procedures are known to have worse outcomes compared to elective ones. Besides, it is conceivable that COVID-19 itself may worsen surgical outcomes due to it may cause respiratory distress and multi-organ dysfunction. We aimed to present patients’ data who underwent surgery due to trauma and emergency general surgery diseases during the COVID-19 pandemic and the effect of COVID-19 on surgical outcomes in this study. Methods: Two hundred and thirty-five patients who underwent surgery due to trauma or emergency between March 2020 and January 2021 were enrolled. Two groups were created according to the COVID-19 status as positive (n=16) and negative (n=219). The demographics, clinical, laboratory, and perioperative data were analyzed and compared between these groups. Results: The median age of the patients was 51 (18-97) years, and 144 (61.2%) of them were male. The most common diagnosis was acute appendicitis (n= 121, 51.5%) followed by ileus. Subgroup comparisons showed that the COVID-19 (+) group had more patients with comorbidity and had higher C-reactive protein values, these differences were significant (p= 0.049, p= 0.001, respectively). Open surgery was performed significantly more in the COVID-19 (+) group (p= 0.037). Serious postoperative complications and mortality were seen more in the COVID-19 (+) group, but the differences were not significant. Patients with COVID-19 had significantly longer hospital stay (p= 0.007). Conclusion: COVID-19 positivity was found to have a negative impact on postoperative surgical outcomes in terms of emergency operations. It is not clear whether this negativity is due to the COVID-19 disease itself or the worse characteristics of patients with COVID-19.
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