阑尾肿瘤的发病率、临床病理特征和肿瘤预后:一项单中心队列研究

IF 0.9 Q4 GASTROENTEROLOGY & HEPATOLOGY
Ferney David Gómez-Báez, Carlos Cerdán-Santacruz, Naroa Moreno Muguiro, Lucía Milla Collado, Mireia Merichal Resina, Jordi Antoni Tarragona Foradada, José Enrique Sierra Grañón, Jorge Juan Olsina Kissler
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引用次数: 0

摘要

阑尾肿瘤是不同肿瘤谱系的大混合体。随着时间的推移,其病理分类的不断演变导致了一些不同的推荐态度。本研究的目的是回顾本院该类肿瘤的发病率、临床病理特点、治疗方法和肿瘤学结果。这是一项单中心回顾性队列研究。每一份被编目为阑尾标本的病理报告在我院进行了为期5年(2013-2017)的审查。记录人口统计学、临床、病理和肿瘤随访数据。对样本进行了描述性研究。共分析了1434例阑尾标本。阑尾肿瘤发生率为3.2%。上皮性肿瘤是主要的组织学亚型,占病例的68%。低度阑尾黏液瘤和神经内分泌肿瘤是最常见的恶性肿瘤,分别为13例和6例。在超过80%的肿瘤病例中,最终的治疗是阑尾切除术。死亡病例与预后非常差和晚期的肿瘤有关。所有患者均进行了充分的肿瘤随访。虽然它仍然相当罕见,但阑尾肿瘤的发病率正在增加,流行病学的变化有利于黏液肿瘤目前占主导地位。因此,有必要了解和使用最新的解剖病理分类,以便在第一或第二手术阶段提供正确的治疗,以及正确的患者随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
Appendiceal tumors represent a large amalgam of different tumor lineages. The continuous evolution in their pathological classifications has led to some variable recommended attitudes over time. The aim of this study is to review the incidence, clinicopathological characteristics, therapeutic approach and oncological results in this type of tumor at our institution. This is a single-centre retrospective cohort study. Every pathologic report catalogued as an appendiceal specimen was reviewed for a time period of 5 years (2013–2017) at our institution. Demographic, clinical, pathological and oncologic follow-up data were recorded. A descriptive study of the sample was completed. A total of 1434 appendiceal specimens was analyzed. Appendiceal neoplasms incidence was 3.2%. Epithelial tumors were the predominant histological subtype, making up 68% of the cases. Low-grade appendiceal mucinous neoplasia and neuroendocrine tumors were the most frequent neoplasms with malignant potential, with 13 and 6 cases, respectively. In more than 80% of neoplasia cases, the definitive treatment was appendectomy. Mortality cases were related to tumors with a very poor prognosis and an advanced stage. All patients had adequate oncological follow-up. Although it is still quite rare, the incidence of appendiceal tumors is increasing with an epidemiological change in favor of mucinous neoplasms currently predominating. Therefore, it is necessary to know and use an updated anatomo-pathological classification in order to provide correct treatment in the first or second surgical stage, as well as the correct follow-up of patients.
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