糖尿病和生活方式队列的血压控制:患者依从性和医生随访行动的作用

Simone L. Dam, Heleen M. Masselink-Haverkate, Christina M. Gant, Stephan J. L. Bakker, Roos M. Nijboer, Willemien J. Kruik-Kollöffel, Gozewijn D. Laverman
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引用次数: 0

摘要

我们研究了在糖尿病和生活方式队列21 -1 (DIALECT-1)中接受二级护理治疗的2型糖尿病(T2D)人群中坚持降压药物治疗(AHT)在血压(BP)控制中的作用。此外,还评估了AHT的强化程度。依从性通过使用药物占有比(MPR)来确定,MPR是根据基线后两年的药房配药数据计算的。依从性定义为MPR≥80%。比较BP-on - target (BP-OT)和BP-not -on - target (BP-not)患者的依从患者比例。在纳入的385例患者中,56%达到了血压目标。BP-OT和BP-NOT的依从患者比例无差异(96% vs 96%;P = 0.91)。在基线后的两年内评估AHT的强化,包括“剂量增加”和“开始使用新药”。在随访期间血压不受控制的患者中,只有37%的患者强化了AHT。总之,AHT的依从性很高,依从性与血压控制之间似乎没有关系。对于未达到血压目标的患者,有机会改善AHT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blood Pressure Control in the DIAbetes and LifEstyle Cohort Twente (DIALECT): The Role of Patient Adherence and Physician’s Follow-Up Action
We studied the role of adherence to antihypertensive drug therapy (AHT) in blood pressure (BP) control in a type 2 diabetes (T2D) population treated in secondary care in the DIAbetes and LifEstyle Cohort Twente-1 (DIALECT-1). In addition, intensification of AHT was assessed. Adherence was determined by using the medication possession ratio (MPR), calculated with pharmacy dispensing data for a period of two years following baseline. Adherence was defined as an MPR ≥ 80%. The proportion of adherent patients was compared between patients who had BP-on target (BP-OT) and BP-not on target (BP-NOT). Of the 385 patients included, 56% achieved their BP target. The proportion of adherent patients did not differ between BP-OT and BP-NOT (96% vs. 96%; p = 0.91). Intensification of AHT, including ‘increase in dosage’ and ‘start of a new drug’, was assessed in the two years following baseline. In only 37% of patients with uncontrolled BP during follow-up was AHT intensified. To conclude, adherence to AHT was high and there does not seem to be a relationship between adherence and BP control. There is an opportunity to improve AHT in patients who do not reach their BP target.
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