特征、态度和对临床试验持积极态度的几率:对印度尼西亚COVID-19疫苗试验参与者的研究

Q2 Medicine
Nani Maharani, Nuvi Gustriawanto, YettyM Nency, Endang Mahati, GlennF Yeremia, DimasT Anantyo, Rebriarina Hapsari, Mulyono Mulyono, SetyoG Pramudo, Nur Farhanah
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引用次数: 0

摘要

目的:本研究旨在了解印度尼西亚人群的特征以及对参与临床试验持更积极态度的因素。方法:对印度尼西亚三宝垄402名COVID-19疫苗试验参与者进行横断面调查,采用自报告问卷,包括与社会人口学特征相关的问题和李克特5量表的陈述,评估对疫苗试验的态度。采用有序Logistic回归分析积极态度的比值,得到奇比和95%置信区间。P < 0.05为差异有统计学意义。结果:调查对象以成人(89.30%)、男性(63.68%)、已婚(77.61%)、在职(59.70%)、从公共卫生服务部门获得临床试验信息(41.29%)、文化程度低(40.80%)、月收入低(68.41%)、未参加临床试验(90.80%)为主。受访者对疫苗试验的态度均较好,受教育程度低、未就业、较少或从未参加过临床试验,从公共卫生中心获得信息是对疫苗试验态度较好的主要预测因素。结论:印尼民众对疫苗试验持积极态度。受教育程度低、未就业、较少或从未参加过临床试验、从公共卫生中心获取信息等因素可以驱动积极态度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characteristics, attitudes, and the odds for positive attitude toward clinical trial: A study on Indonesian COVID-19 vaccine trial participants
Aims: This study was performed to understand the Indonesian population’s characteristics and the factors that contribute to a more positive attitude toward participation in a clinical trial. Methods: A cross-sectional survey was conducted involving 402 COVID-19 vaccine trial participants in Semarang, Indonesia, utilizing self-reporting questionnaires consisting of questions related to socio-demographic characteristics and statements in a 5-scaled Likert Scale to assess the attitude toward vaccine trial. The odds for positive attitude were analyzed using Ordinal Logistic Regression to obtain the odd-ratio and 95% confidence interval. The P < 0.05 was considered statistically significant. Results: Most of the respondents were adults aged 22–64-year-old (89.30%), males (63.68%), married (77.61%), worked as an employee (59.70%), obtained information about the clinical trial from the Public Health Service (41.29%), had a low education level (40.80%), a low monthly income level (68.41%), with no previous participation in a clinical trial (90.80%). All respondents showed a good attitude toward the trial, with low education level, nonemployment status, fewer or no previous participation in clinical trials, and getting the information from the public health centers were the main predictors for better attitude toward vaccine trials. Conclusion: There was a positive attitude toward vaccine trials in the Indonesian population. The positive attitude could be driven by having a low education level, nonemployment status, fewer or no previous participation in the clinical trial, and getting information from public health centers.
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来源期刊
Perspectives in Clinical Research
Perspectives in Clinical Research Medicine-Medicine (all)
CiteScore
2.90
自引率
0.00%
发文量
41
审稿时长
36 weeks
期刊介绍: This peer review quarterly journal is positioned to build a learning clinical research community in India. This scientific journal will have a broad coverage of topics across clinical research disciplines including clinical research methodology, research ethics, clinical data management, training, data management, biostatistics, regulatory and will include original articles, reviews, news and views, perspectives, and other interesting sections. PICR will offer all clinical research stakeholders in India – academicians, ethics committees, regulators, and industry professionals -a forum for exchange of ideas, information and opinions.
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