透过小孔窥视:结核性葡萄膜炎的有趣过程

Priyanka Gupta, Anupriya Aggarwal, Akriti Sehgal
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引用次数: 0

摘要

病例史30岁女性,右眼视力减退。最佳矫正视力(BCVA)为6/60 OD(右眼)和6/6 OS(左眼)。她正在接受肺结核的抗结核治疗。她的诊断是通过支气管肺泡灌洗(BAL)培养和典型的计算机断层扫描结果确定的。右眼检查发现前房(AC)反应+2,Koeppe和Busaca结节,并伴有多发后粘连,特征性瞳孔扩张,未成熟白内障,2级玻璃体炎。左眼没什么特别的。询问了患者的详细病史,并进行了系统检查,以排除病毒和其他原因引起的葡萄膜炎。除了抗结核治疗外,她还接受了局部和全身类固醇治疗。该患者未能随访。然而,3个月后,她出现了安静的AC和虹膜内多发、界限分明、不规则但同心的透照缺陷,这是由虹膜色素上皮变性和间质变薄引起的[图1]。图1裂隙灯图像(a)急性葡萄膜炎期伴有虹膜结节(b)有多个透照缺陷的消退期。在Fuchs异色虹膜睫状体炎、Fuchs葡萄膜综合征、Vogt-Koyanagi-Harada病、色素分散综合征、假性脱落综合征和创伤中均可见ris萎缩斑块。[1]这种结核性葡萄膜炎的透照缺陷是罕见的,然而,偶尔也有报道。[2]在这里,我们报告了这个独特的结核性葡萄膜炎病例,抗结核治疗和类固醇反应良好,导致炎症消退,但留下了虹膜萎缩斑块。患者同意声明作者证明他们已经获得了所有适当的患者同意表格。在表格中,患者已经同意他/她/他们的图像和其他临床信息将在杂志上报道。患者明白他们的姓名和首字母不会被公布,并将尽力隐藏他们的身份,但不能保证匿名。财政支持及赞助无。利益冲突没有利益冲突。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Peeping through the holes: An interesting course of tubercular uveitis
CASE HISTORY A 30-year-old female presented with diminished vision in her right eye. Her best corrected visual acuity (BCVA) was 6/60 OD (Right eye) and 6/6 OS (Left eye). She was on antitubercular therapy for pulmonary Kochs. Her diagnosis was established by bronchoalveolar lavage (BAL) culture and typical computed tomography findings. Right eye examination revealed anterior chamber (AC) reaction +2, Koeppe’s and Busaca’s nodules, along with multiple posterior synechiae, characteristic festooned pupil on attempted dilatation, immature cataract, and grade 2 vitritis. The left eye was unremarkable. Her detailed history was elicited and systemic examination was done to rule out viral and other causes of uveitis. She was put on topical and systemic steroids along with cycloplegics, in addition to her antitubercular therapy. The patient was lost to follow-up. However, she presented 3 months later with quiet AC and multiple, well-defined, irregular but concentric transillumination defects in iris, caused by iris pigment epithelium degeneration and thinning of stroma [Figure 1].Figure 1: Slit lamp image in (a) acute uveitis phase with iris nodules (b) resolved phase with multiple transillumination defectsIris atrophic patches have been seen in Fuchs heterochromic iridocyclitis, Fuchs uveitic syndrome, Vogt-Koyanagi-Harada disease, pigment dispersion syndrome, pseudoexfoliation syndrome, and trauma.[1] Such transillumination defects in tubercular uveitis are rare and, however, have been occasionally reported.[2] Here, we present this unique case of tubercular uveitis which responded well to antitubercular therapy and steroids, resulting in resolution of inflammation, but leaving behind patches of iris atrophy. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.
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