一种糖肽在体内对肝细胞周期的体外影响。

Cell and tissue kinetics Pub Date : 1987-09-01 DOI:10.1111/j.1365-2184.1987.tb01358.x

M N Lombard, C Nadal, M J Monnot

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引用次数: 3

摘要

在体内发现了一种特异性抑制肝细胞周期的因子，可在体外阻断肝细胞的G1-S转变。根据对细胞增殖的可逆性判断，在我们的培养条件下，它被证明是无毒的。对成纤维细胞系(3T3) DNA合成无活性。

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In vitro effect of a glycopeptide acting in vivo on hepatocyte cell cycle.

A factor specifically inhibiting the hepatocyte cell cycle in vivo was found to block the G1-S transition of liver cells in vitro. It proved to be non-toxic in our culture conditions, as judged by the reversibility of the effect on cell proliferation. It was not active on DNA synthesis in fibroblastic cell lines (3T3).

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Cell and tissue kinetics

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