辣椒叶油的化学成分及抗乙酰胆碱酯酶活性

HPU2 Journal of Science Natural Sciences and Technology Pub Date : 2023-08-31 DOI:10.56764/hpu2.jos.2023.2.2.41-47

Thuy -Van Do Thi, Ngoc-Linh Nguyen, Anh-Hung Nguyen

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引用次数: 0

摘要

采用水蒸气蒸馏法提取广南-岘港胡椒叶精油，集油率达0.68%。采用气相色谱-质谱联用法测定了广南岘港地区辣椒叶精油的化学成分，共鉴定出20种成分(99.97%)，其中主要成分为肉豆蔻素(72.70%)、茜草酮(5.16%)、β-bisabolene(3.59%)、γ-茜草酮(3.52%)、石竹烯(2.63%)和α-copaene(1.93%)。与阳性对照加兰他明和胡椒精油相比，广南岘港胡椒叶精油也表现出较强的抗乙酰胆碱酯酶活性，IC50(µg/mL) = 28.72±2.80

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Chemical components and anti-acetylcholinesterase activity of Piper lolot leaves oil

Essential oil of Piper lolot leaves in Quang Nam-Da Nang do obtain via the steam distillation method with oil collection efficiency reaching 0.68%. The chemical components of the essential oil from Piper lolot leaves in Quang Nam-Da Nang are determined via the GC-MS method that includes 20 compositions (99.97%), among which the main compositions are myristicin (72.70%), asarone (5.16%), β-bisabolene (3.59%), γ-asarone (3.52%), caryophyllene (2.63%), and α-copaene (1.93%). The essential oil of Piper lolot leaves in Quang Nam-Da Nang also showed potent anti-acetylcholinesterase activity with IC50 (µg/mL) = 28.72±2.80 compared to galantamine (a positive control) and essential oils, extract from Piper species

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HPU2 Journal of Science Natural Sciences and Technology

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