l -天冬酰胺酶修饰形式的免疫化学研究。

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology Pub Date : 1987-11-01

M F Iulaev, D M Ivnitskiĭ, A P Kashkin, T Ia Bogdanova, A S Korsakova

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摘要

研究了聚葡聚糖修饰l -天冬酰胺酶的催化和免疫特性。结果表明，改性后的l -天冬酰胺酶保持了较高的催化活性(Km 0.0.810 (-5)-1.89.10(-5) M)，同时在抗体作用下表现出更强的抗失活能力。

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[Immunochemical study of modified forms of L-asparaginase].

Certain catalytic and immunological properties of L-asparaginase modified by polyglucin were studied. It was shown that the modified forms of L-asparaginase maintained high catalytic activity (Km 0.80.10(-5)-1.89.10(-5) M) and at the same time appeared to be more resistant to inactivation under the effect of antibodies.

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Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology

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