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{"title":"编辑对相关科学出版物的选择","authors":"","doi":"10.1158/1940-6207.capr-16-8-hfl","DOIUrl":null,"url":null,"abstract":"Highlights from the Literature| August 01 2023 Editors' Selections from Relevant Scientific Publications Author & Article Information Online ISSN: 1940-6215 Print ISSN: 1940-6207 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Prev Res (Phila) (2023) 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record August 1 2023 Citation Editors' Selections from Relevant Scientific Publications. Cancer Prev Res (Phila) 1 August 2023; 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Polygenic risk scores for screening (from Centers for Disease Control and Prevention) Using UK metrics, Huntley et al. conducted a modeling analysis on the performance of polygenic risk score (PRS) tools and PRS-stratified cancer screening. They estimated the potential annual numbers of cancer cases detected and deaths averted for eight different cancers. The results suggested that, under favorable assumptions, hypothetical PRS-stratified screening programs could modestly improve efficiency for three cancer types. Specifically, they could reduce maximum number of annual deaths from 102 to 80 for breast cancer, 188 to 155 for prostate cancer, and 158 to 95 for colorectal cancer. However, UK-specific cluster-randomized trials are required to evaluate the real-world clinical impact, costs, and potential harm of PRS stratification. Huntley C, … Turnbull C. Lancet Oncol. 2023 Jun;24(6): 658-668. Illustration of deep learning (by OpenClipart via FreeSVG) Pancreatic cancer is often diagnosed too late to achieve good clinical outcomes,... You do not currently have access to this content.","PeriodicalId":9373,"journal":{"name":"Cancer Prevention Research","volume":"43 1","pages":"0"},"PeriodicalIF":2.9000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Editors' Selections from Relevant Scientific Publications\",\"authors\":\"\",\"doi\":\"10.1158/1940-6207.capr-16-8-hfl\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Highlights from the Literature| August 01 2023 Editors' Selections from Relevant Scientific Publications Author & Article Information Online ISSN: 1940-6215 Print ISSN: 1940-6207 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Prev Res (Phila) (2023) 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record August 1 2023 Citation Editors' Selections from Relevant Scientific Publications. Cancer Prev Res (Phila) 1 August 2023; 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Polygenic risk scores for screening (from Centers for Disease Control and Prevention) Using UK metrics, Huntley et al. conducted a modeling analysis on the performance of polygenic risk score (PRS) tools and PRS-stratified cancer screening. They estimated the potential annual numbers of cancer cases detected and deaths averted for eight different cancers. The results suggested that, under favorable assumptions, hypothetical PRS-stratified screening programs could modestly improve efficiency for three cancer types. Specifically, they could reduce maximum number of annual deaths from 102 to 80 for breast cancer, 188 to 155 for prostate cancer, and 158 to 95 for colorectal cancer. However, UK-specific cluster-randomized trials are required to evaluate the real-world clinical impact, costs, and potential harm of PRS stratification. Huntley C, … Turnbull C. Lancet Oncol. 2023 Jun;24(6): 658-668. Illustration of deep learning (by OpenClipart via FreeSVG) Pancreatic cancer is often diagnosed too late to achieve good clinical outcomes,... 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Editors' Selections from Relevant Scientific Publications
Highlights from the Literature| August 01 2023 Editors' Selections from Relevant Scientific Publications Author & Article Information Online ISSN: 1940-6215 Print ISSN: 1940-6207 ©2023 American Association for Cancer Research2023American Association for Cancer Research Cancer Prev Res (Phila) (2023) 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Article Versions Icon Versions Version of Record August 1 2023 Citation Editors' Selections from Relevant Scientific Publications. Cancer Prev Res (Phila) 1 August 2023; 16 (8): 419. https://doi.org/10.1158/1940-6207.CAPR-16-8-HFL Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest Search Advanced Search Polygenic risk scores for screening (from Centers for Disease Control and Prevention) Using UK metrics, Huntley et al. conducted a modeling analysis on the performance of polygenic risk score (PRS) tools and PRS-stratified cancer screening. They estimated the potential annual numbers of cancer cases detected and deaths averted for eight different cancers. The results suggested that, under favorable assumptions, hypothetical PRS-stratified screening programs could modestly improve efficiency for three cancer types. Specifically, they could reduce maximum number of annual deaths from 102 to 80 for breast cancer, 188 to 155 for prostate cancer, and 158 to 95 for colorectal cancer. However, UK-specific cluster-randomized trials are required to evaluate the real-world clinical impact, costs, and potential harm of PRS stratification. Huntley C, … Turnbull C. Lancet Oncol. 2023 Jun;24(6): 658-668. Illustration of deep learning (by OpenClipart via FreeSVG) Pancreatic cancer is often diagnosed too late to achieve good clinical outcomes,... You do not currently have access to this content.