经颅磁刺激的历史和基本原理

Luis Lopez Chau, Michael Kabar
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摘要

经颅磁刺激(TMS)是一种利用磁场刺激大脑皮层神经元的非侵入性技术。虽然电以前被打算用于医疗领域,但经颅磁刺激的历史可以追溯到19世纪法拉第发现电磁感应。然而,直到20世纪80年代,安东尼·巴克才在谢菲尔德大学开发了第一台经颅磁刺激装置。TMS的工作原理是在头皮上放置一个线圈,从而产生一个磁场。这个磁场可以穿过颅骨,刺激皮层神经元。磁场的强度和频率可以调整,以针对大脑的特定区域,并产生兴奋和抑制作用。经颅磁刺激的原理是基于神经可塑性的概念,即大脑对新体验和刺激的改变和适应能力。通过颅磁刺激刺激大脑中的神经元,有可能引起神经元活动和连通性的变化,从而导致认知和情绪变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Historia y principios básicos de la estimulación magnética transcraneal
Transcranial magnetic stimulation (TMS) is a noninvasive technique that uses magnetic fields to stimulate neurons in the cerebral cortex.While electricity has previously been intended to be used in the medical field, the history of TMS dates back to the discovery of electromagnetic induction by Faraday in the 19th century. However, it was not until the 1980s when Anthony Barker developed the first TMS device at the University of Sheffield.TMS works by means of a coil placed against the scalp, thereby producing a magnetic field. This magnetic field can pass through the skull and stimulate cortical neurons. The intensity and frequency of the magnetic field can be adjusted to target specific areas of the brain and produce excitatory and inhibitory effects.The principles of TMS are based on the concept of neuroplasticity, which refers to the brain’s ability to change and adapt in response to new experiences and stimuli. By stimulating neurons in the brain with TMS, it is possible to cause changes in neuronal activity and connectivity, which in turn can lead to cognitive and mood changes.
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