博莱霉素抗肿瘤治疗短期高血糖的疗效观察。

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology Pub Date : 1987-07-01

S E Ul'ianenko, V M Petriev, A N Dedenkov

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摘要

对45号肉瘤大鼠的实验研究表明，博莱霉素可通过诱导短期高血糖显著提高抗肿瘤效果。结果表明，各因素加和效应的理论值低于实验值。这有利于博莱霉素在高血糖条件下的协同作用机制。

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[Effectiveness of the antitumor action of bleomycetin in short-term hyperglycemia].

Experimental studies on rats with sarcoma 45 showed that antitumor efficacy of bleomycetin could be markedly increased by inducing short-term hyperglycemia. It was noted that the theoretical value of the additive effect of these factors was lower than the experimental one. This is in favour of the synergistic mechanism of bleomycetin action under conditions of hyperglycemia.

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Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology

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