氨苄西林在前列腺腺瘤患者中的药代动力学研究。

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology Pub Date : 1987-07-01

V P Iakovlev, L Z Skala, R A Slobodskoĭ, A G Nekhorosheva, L A Lur'e

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摘要

前列腺腺瘤患者氨苄西林药代动力学研究表明，腺瘤不影响抗生素动力学。氨苄西林在尿液组织和器官中的最高浓度与血液中的最高浓度相对应。因此，提供尿路组织和器官中药物有效浓度的给药方案的发展应基于氨苄西林在血液中的动力学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Ampicillin pharmacokinetics in prostatic adenoma patients].

Studies on ampicillin pharmacokinetics in patients with prostate adenoma showed that adenoma did not influence the antibiotic kinetics. The ampicillin maximum concentration in tissues and organs of the urinary corresponded to the peak concentrations in blood. Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood.

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Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology

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