{"title":"纳米体作为靶向给药系统的研究进展","authors":"K Pooja, S B Shirsand","doi":"10.26463/rjps.13_3_7","DOIUrl":null,"url":null,"abstract":"Due to a lack of effective treatment factor or drug delivery systems many diseases go untreated especially when side effects and toxicities are the main cause of concern. Consequently we chose novel drug delivery system. The structure of niosomes is made up of three moieties hydrophilic amphiphilic and lipophilic which can accommodate several drug molecules with a wide range of solubilities. Niosomes are preferred over liposomes because of the non-ionic surfactants higher stability lower cost and ease of storage compared to phospholipids. Surfactants do not require any particular handling or storage conditions. Niosomes act as a controlled and targeted drug delivery system that reduces toxicity and increases drug penetration into target tissues. The review article focused on several ideas including advantages and disadvantages of niosomal preparations niosome characteristics and its application.","PeriodicalId":21459,"journal":{"name":"RGUHS Journal of Pharmaceutical Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Advances of Niosomes as a Targeted Drug Delivery Syste\",\"authors\":\"K Pooja, S B Shirsand\",\"doi\":\"10.26463/rjps.13_3_7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Due to a lack of effective treatment factor or drug delivery systems many diseases go untreated especially when side effects and toxicities are the main cause of concern. Consequently we chose novel drug delivery system. The structure of niosomes is made up of three moieties hydrophilic amphiphilic and lipophilic which can accommodate several drug molecules with a wide range of solubilities. Niosomes are preferred over liposomes because of the non-ionic surfactants higher stability lower cost and ease of storage compared to phospholipids. Surfactants do not require any particular handling or storage conditions. Niosomes act as a controlled and targeted drug delivery system that reduces toxicity and increases drug penetration into target tissues. The review article focused on several ideas including advantages and disadvantages of niosomal preparations niosome characteristics and its application.\",\"PeriodicalId\":21459,\"journal\":{\"name\":\"RGUHS Journal of Pharmaceutical Sciences\",\"volume\":\"22 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"RGUHS Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26463/rjps.13_3_7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"RGUHS Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26463/rjps.13_3_7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Advances of Niosomes as a Targeted Drug Delivery Syste
Due to a lack of effective treatment factor or drug delivery systems many diseases go untreated especially when side effects and toxicities are the main cause of concern. Consequently we chose novel drug delivery system. The structure of niosomes is made up of three moieties hydrophilic amphiphilic and lipophilic which can accommodate several drug molecules with a wide range of solubilities. Niosomes are preferred over liposomes because of the non-ionic surfactants higher stability lower cost and ease of storage compared to phospholipids. Surfactants do not require any particular handling or storage conditions. Niosomes act as a controlled and targeted drug delivery system that reduces toxicity and increases drug penetration into target tissues. The review article focused on several ideas including advantages and disadvantages of niosomal preparations niosome characteristics and its application.