目前乳腺癌患者淋巴水肿治疗的概念:临床实践回顾

Tal Tobias, Assaf A. Zeltzer
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引用次数: 1

摘要

摘要淋巴水肿是由淋巴引流不足导致软组织间质液异常积聚而引起的一种进行性疾病。在发达国家,继发性淋巴水肿最常见的原因是乳腺癌的治疗。在过去,这几乎是一种被遗忘的疾病,经常被忽视,如今我们可以为患者提供治疗和救济。我们从临床诊断出发,通过不同的影像学方式探讨目前乳腺癌患者淋巴水肿的治疗方法及其优缺点。可能的保守和手术治疗旨在恢复淋巴功能和减少脂肪肥大。从切除术或吸脂等还原性技术到包括重建显微手术的生理性技术,如淋巴-静脉吻合(LVA)、血管化淋巴结转移(VLNT)和其他淋巴自由皮瓣。从2005年到现在,我们对乳腺癌患者继发性淋巴水肿的治疗方法和指南进行了综述。它是基于我们不断增长的经验和不断发展的技术。乳腺癌患者淋巴水肿的治疗是多学科的,包括普通外科医生、整形外科医生、肿瘤学家、物理治疗师、社会工作者等等。提倡对病人采取全面的治疗方法。这最好通过调整和定制适合每个病人的治疗来实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current concepts of lymphedema treatment for the breast cancer patient: a clinical practice review
Abstract: Lymphedema is a progressive disease caused by insufficient lymphatic drainage leading to abnormal accumulation of interstitial fluid within soft tissues. The most common cause for secondary lymphedema in the developed world is treatment for breast cancer. In the past, almost a forgotten disease, frequently overlooked, nowadays we can provide patients with treatment and relief. We discuss the current approach to lymphedema treatment for the breast cancer patient from clinical diagnosis through different imaging modalities with their advantages and disadvantages. Possible conservative and operational treatments aimed to restore lymphatic function and reduce adipose hypertrophy are described. From reductive techniques such as resection or liposuction to physiologic techniques involving reconstructive microsurgery such as lymphatico-venous anastomosis (LVA), vascularized lymph node transfer (VLNT) and other lymphatic free flaps. A review of our constructed approach and guidelines for managing secondary lymphedema in the breast cancer patient from 2005 to present days is presented. It is based on our growing experience and evolving techniques. Management of lymphedema in the breast cancer patient is multi-disciplinary and involves both the general and plastic surgeons, oncologists, physical therapists, social workers and many more. A holistic approach to the patient is advocated. This is best performed by adjusting and tailoring the appropriate treatment for each patient.
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