呋喃妥因致可逆性间质性肺病

Shabana Ashraf, Sajid Salahudheen
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摘要

摘要:药物性肺间质性疾病是一种越来越常见的发病和死亡原因。呋喃妥因是一种广谱抗生素,用于急性无并发症或单纯性膀胱炎以及预防复发性感染。我们最近遇到了一例呋喃妥因引起的间质性肺部疾病,这是一位因反复尿路感染而服用呋喃妥因一年半的老年患者。经进一步评估,她被诊断为药物性间质性肺病,并经影像学证实。停用呋喃妥因,并用低剂量全身糖皮质激素治疗。本病例报告强调需要密切警惕长期服用呋喃妥因治疗的患者的肺毒性。关键词:肺毒性,皮质类固醇,呋喃妥因,间质性肺疾病,尿路感染
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nitrofurantoin Induced Reversible Interstitial Lung Disease
Abstract: Drug-induced interstitial lung disease is an increasingly common cause of morbidity and mortality. Nitrofurantoin is a broad-spectrum antibiotic used for acute uncomplicated or simple cystitis as well as for prophylaxis of recurrent infection. We recently encountered a case of Nitrofurantoin-induced interstitial lung disease in an elderly patient who was on Nitrofurantoin for a year and a half for recurrent urinary tract infections. On further evaluation, she was diagnosed with drug-induced interstitial lung disease, which was confirmed by radiographic evidence. Nitrofurantoin was discontinued and managed with low-dose systemic glucocorticoids. This case report highlights the need for close vigilance of pulmonary toxicities in patients taking long-term Nitrofurantoin therapy. Keywords: Pulmonary toxicity, Corticosteroids, Nitrofurantoin, Interstitial Lung disease, Urinary tract infection.
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