基于二维斑点跟踪技术的原发性高血压早期左室重构患者左房功能研究

Lingling Wang, Jing Dong, Wenfang Wu, Pingyang Zhang
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摘要

目的:利用二维散斑跟踪成像(2D-STI)分析高血压早期左室构型肥厚改变前左心房的功能变化,探讨该技术在评价高血压患者左心房特征变化中的临床价值。方法:招募临床诊断及常规超声检查符合本研究要求的原发性高血压患者70例,按甘南法分为两组:左室标准重构组38例,左室同心重构组32例,随机选择年龄、性别匹配的健康人群40例作为对照组。利用2D-STI获取各组左心房收缩期、舒张早期和舒张晚期的平均峰值应变和应变率。采用上述参数和指标进行对比分析。结果:与健康对照组比较,重构组和重构组舒张早期峰值应变值和应变率均有统计学差异;与标准重塑组相比,同心重塑组各时期的峰值应变和应变速率值均有显著差异(P <0.05)。结论:2D-STI能更灵敏、方便地反映早期原发性高血压患者左房心肌的特征性变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study on Left Atrial Function in Patients with Early Left Ventricular Remodeling in Essential Hypertension Based on Two-Dimensional Speckle Tracking Technology
Objective: To use two-dimensional speckle tracking imaging (2D-STI) to analyze the functional changes of the left atrium before hypertrophic changes in the left ventricular configuration in the early stage of hypertension and to explore the clinical value of this technology in evaluating the changes of left atrial characteristics in patients with hypertension. Methods: 70 cases of patients with essential hypertension who met the requirements of this study after clinical diagnosis and routine ultrasound examination were recruited and divided into two groups according to the Ganan method: 38 cases in the left ventricular standard remodeling group, 32 cases in the left ventricular concentric remodeling group, and 40 healthy people with matched age and sex were randomly selected as the control group. The mean peak strains and strain rates of the left atrial systole, early diastole, and late diastole of each group were obtained using 2D-STI. The above parameters and indicators were used for comparative analysis. Results: Compared with the healthy control group, the values of peak strains and strain rates during early diastole were statistically different in both remodeling groups; compared with the standard remodeling group, the values of peak strains and strain rates in all periods were significantly different in the concentric remodeling group (P < 0.05). Conclusion: 2D-STI can be more sensitive and convenient to reflect the characteristic changes of left atrial myocardium in patients with early essential hypertension.
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