Comparative Study on Biochemical Effects of Natural and Synthetic Pesticides on Preserved Phaseolus lunatus in Male Albino Rats

The legume Phaseolus lunatus production is hindered by pest infestation which may have reduced its quality and quantity. To this effect, pesticides come into play to kill these pests. The purpose of the study was to determine how various preservatives affected the biochemistry of male albino rats. Exactly 36 male albino rats of 200-250 g were grouped into six. They were fed with a dietary intervention for 8 weeks with 4 different methods of selected preserved diets. The groups are Group 1 (normal control) was rats administered only feed and water. Group 2 (blank) was rats administered only Phaseolus lunatus without preservative. Group 3 was rats administered feeds + Phaseolus lunatus preserved with aluminium phosphide. Group 4 was rats administered feeds + Phaseolus lunatus preserved with pepper. Group 5 was rats administered feed + Phaseolus lunatus preserved with dichlorvos. Group 6 was rats administered feed + Phaseolus lunatus preserved with wood ash. The result showed significant increase in AST and ALT of lima beans preserved with pepper (23.67±2.47c) (15.38±1.55a) P<0.01 and ash (34.51 2.04d) (15.12±3.10a) P<0.001, respectively. When albino rats were given beans preserved in ash, their CRP levels increased noticeably P<0.05 (69.94±1.64b) (62.97±5.30a). PCV and platelet levels in albino rats given lima beans preserved with ash significantly decreased P< 0.01 (39.00±1.00c) (49.92±5.48a) and P<0.001 (95.54±3.45d) (213.31±32.31a), respectively. The majority of renal function metrics show considerable increases. In conclusion, the study revealed the alteration in the biochemical parameters of the albino rats after consumption of the preserved beans, this may indicate cellular damage.