55岁印度女性骨密度测定

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
ArunKumar R. Pande, Sanjay Kalra
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引用次数: 0

摘要

骨质疏松症是一种通过骨密度(BMD)检查来诊断的骨骼疾病。通过BMD诊断骨质疏松,我们需要关注报告中的T-score和Z-score值。T-score是受试者骨密度值与峰值骨密度(即年轻个体骨密度)的标准差(SD)。t值小于或等于- 2.5被认为是骨质疏松症的提示。Z-score是同一年龄组受试者骨密度值的标准差。Z-score值≤2.0被认为是低骨密度的提示。骨密度是指每块骨头中矿物质的含量,个子矮的人骨密度与个子高的人不同。印度人的平均身高比高加索人矮。为了缓解这一问题,收集了BMD参考数据;印度医学研究委员会进行了一项以社区为基础的多中心研究,以获得印度对峰值骨量的参考。[1]T-score为峰值骨量的SD值,Z-score为同年龄个体的SD值。在特定患者中,t评分不可能达到- 1.7,z评分不可能达到- 3.3。我们想强调的是一份55岁女性的骨密度报告,她用GE Lunar DPX DEXA脊柱骨密度仪测量骨密度,结果为0.903 g/cm2, t评分为- 1.7,结果显示81%的骨密度为年轻。如果我们反向计算峰值骨量或年轻人的骨密度平均值,结果为1.115 g/cm2。同一患者的z得分为- 3.3,结果也显示了69%的平均或峰值年龄匹配的BMD。如果我们反算年龄匹配的骨密度平均值为1.309 g/cm2。年龄匹配的骨密度不能大于年轻时的峰值骨。要么是数据有缺陷,要么是参考数据不具有代表性。然而,在我们的实践中,我们仍然看到这样的报告,特别是在55岁及左右的女性中。由于Z-score≤2.0,我们必须检查骨质疏松的继发原因。所有的调查结果都是否定的。这浪费了治疗医生的时间,并增加了患者在接受此类调查期间的压力和经济负担。患者同意声明作者证明他们已经获得了所有适当的患者同意表格。以患者同意在期刊上报道其图像和其他临床信息的形式。患者明白他们的姓名和首字母不会被公布,并将尽力隐藏他们的身份,但不能保证匿名。财政支持和赞助利益冲突没有利益冲突。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bone mineral densitometry in a 55-year-old Indian female
Osteoporosis is a condition of the bone, which is diagnosed by performing bone mineral density (BMD) investigation. To diagnose osteoporosis on BMD, we have to focus on T-score and Z-score values on the report. T-score is the standard deviation (SD) of the BMD value of the subject from peak bone mass that is BMD of young age individual. A value T-score less than or equal to −2.5 is considered to be suggestive of osteoporosis. Z-score is the SD of the BMD value from the subject same age group. A value Z-score ≤2.0 is considered to be suggestive of low BMD. As BMD value the mass of mineral per volume of bone, those individual who are shorter their BMD varies as compared to those who are taller. Average Indians are shorter in height as compared to Caucasians. To mitigate this issue, BMD reference data were collected; the Indian Council of Medical Research conducted a community-based multicenter study to derive Indian references for peak bone mass.[1] As T-score is the SD of BMD from peak bone mass and Z-score is the SD BMD from individuals of the same age. It is impossible to have a T-score of −1.7 and Z-score of −3.3 in a particular patient. We want to highlight a BMD report of 55-year-old female whose BMD was performed by GE Lunar DPX DEXA machine for spine BMD, which came out to be 0.903 g/cm2 with T-score of −1.7 also the result shows 81% of BMD of young age. If we back calculate the mean of BMD of peak bone mass or of a young age person, it comes out to 1.115 g/cm2. The Z-score of the same patient comes out to be −3.3 and the result also shows 69% of mean or peak age-matched BMD. If we back calculate the mean of BMD of age matched, it comes to 1.309 g/cm2. BMD of age matched cannot be greater than that of peak bone of young age. Either there is a flaw in the data or the reference data are not representative. However, we still see such reports in our practice, especially in females of age 55 years and around. As the Z-score is ≤2.0, we have to check for secondary causes of osteoporosis. All investigation comes out negative. This wastes the time of treating physicians and adds to the stress and financial burden to the patient, during the time, they are undergoing such investigations. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship None. Conflicts of interest There are no conflicts of interest.
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来源期刊
Indian Journal of Medical Specialities
Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-
自引率
16.70%
发文量
51
期刊介绍: The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.
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