M. Sangeetha, J. Banurekha, C. Mahendran, S. V. Muruganatham
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引用次数: 0
摘要
纵观人类历史,植物的生物活性化学物质一直被用作补充剂和药物,以支持人体的自然生理过程。当它们的功能被发现时,许多物质被添加到医疗用途中。众所周知,草药含有多种有机物质。这些重要的草药是许多药品和保健产品的主要成分。传统的民间医学实践也为许多药物和活动的提取和创造提供了重要的信息。一些高活性药物的生产是通过从绿色工厂提取和表征各种生物活性化学物质来证明的。本研究使用醋酸乙酯、乙醇、正己烷、氯仿和水萃取物的定量分析,以及既定的方法来评估植物化学物质。在定量和植物化学筛选结果中发现了生物碱、黄酮类、还原糖、蛋白质、氨基酸、皂苷、单宁、萜类和苷类。由于几种植物化学物质的存在,整个Psychotria octosulcata W. a . Talbot植物显示出多种药用潜力。采用盐水对虾致死试验(BSLA)预测植物提取物的细胞毒活性。结果表明,在较高浓度下,对虾类有极大危害。在最低浓度下,即使在24小时后,也只有10只虾是致命的。这可能是由于生物活性物质的存在。
Phytochemical Evaluation of Different Solvent Mediated Extracts and Brine Shrimp Lethality Bioassay of Psychotria Octosulcata W.A Talbot
Plants’ bioactive chemicals have been utilized throughout human history as supplements and medicines to support the body’s natural physiological processes. When their function is discovered, many substances are added for medical uses. Herbs are known to contain a variety of organic substances. These crucial herbs are the main ingredients in many pharmaceutical and healthcare products. Traditional folk medical practices offer essential information for the extraction and creation of numerous medications and activities as well. The production of a few highly active pharmaceuticals is justified by the extraction and characterization of a variety of bioactive chemicals from green factories. This study uses quantitative analysis of ethyl acetate, ethanol, n-hexane, chloroform and aqueous extract along with established methodologies to assess the phytochemicals. Alkaloids, flavonoids, reducing sugars, proteins, amino acids, saponins, tannins, terpenoids and glycosides were discovered in the quantification and phytochemical screening results. Due to the presence of several phytochemical substances, the entire plant of Psychotria octosulcata W. A. Talbot demonstrated a diversity of medicinal potential. The cytotoxicity activity of the plant extracts was predicted using brine shrimp lethality assay (BSLA). The results showed that the shrimp in the ethanolic extract of Psychotria octosulcata W. A. Talbotare extremely hazardous in higher concentrations. Only 10 shrimps are discovered to be lethal at lowest concentrations even after 24 h. This can be due to the presence of bioactive substances.
期刊介绍:
This inter-disciplinary, internationally-reviewed research journal covers all aspects of nanometer scale science and technology. Articles in any contemporary topical areas are sought, from basic science of nanoscale physics and chemistry to applications in nanodevices, quantum engineering and quantum computing. IJN will include articles in the following research areas (and other related areas): · Properties Effected by Nanoscale Dimensions · Atomic Manipulation, Coupling of Properties at the Nanoscale · Controlled Synthesis, Fabrication and Processing at the Nanoscale · Nanoscale Precursors and Assembly, Nanostructure Arrays, Fullerenes, Carbon Nanotubes and Organic Nanostructures · Quantum Dots, Quantum Wires, Quantum Wells, Superlattices