Omneya Elbakry, Marwa Harras, Mohamed Elsebaei, Ahmed Mehany, Hend Elsehrawi
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Development of pyrazolo[1,5-a]pyrimidine derivatives: Synthesis, anticancer activity and docking study
: It has been revealed that scaffolds made from pyrazolo[1,5-a]pyrimidines exhibit valuable biological activities, particularly anti-proliferative efficacy and blocking CDK activity. Therefore, new derivatives of pyrazolo[1,5-a]pyrimidines 5a-c were synthesized, and their chemical structures were validated using several spectral studies. These compounds were screened against MCF-7, HCT-116
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