Diarrhea syndrome: current aspects of differential diagnosis and treatment at the stage of primary health care

Diarrhea is one of the most common syndromes encountered in the practice of a general practitioner, a general practitioner, a pediatrician at the stage of providing primary health care, as well as a gastroenterologist, an infectious disease specialist and a surgeon at the stage of providing specialized medical care. The first part of the review is devoted to the differential diagnosis of diarrhea, the main pathological conditions and nosological forms in which the development of diarrhea syndrome is possible in real clinical practice are considered. The second part of the review is devoted to a promising active method in gastroenterological practice-enterosorption. The main requirements for modern enterosorbents are met by the domestic enterosorbent based on silica (colloidal silicon dioxide) Polysorb® MP. Its properties are considered, data of comparative studies with other enterosorbents are given. The studies demonstrating the efficacy and safety of the use of enterosorbent Polysorb® MP in the complex therapy of infectious diarrhea in adult patients and in pediatric practice are presented. Diarrhea is one of the most common gastrointestinal symptoms in the new coronavirus infection COVID-19. A number of studies have noted the effectiveness of the use of colloidal silicon dioxide (Polysorb® MP) in the complex treatment of adults and children with COVID-19 and as part of the post-COVID syndrome. The use of Polysorb® MP helps to reduce the viral load in the intestine, reduce diarrhea and other clinical symptoms of gastrointestinal lesions in COVID-19. Availability of modern effective and safe enterosorbent Polysorb® MP in the arsenal of a doctor at the stage of providing primary health care will optimize drug therapy in patients with diarrhea syndrome and other comorbid somatic pathologies.