{"title":"l -天冬酰胺酶与Pegaspargase治疗成人急性淋巴细胞白血病的疗效比较","authors":"Limin Hou, Lan Li","doi":"10.26689/par.v7i5.5157","DOIUrl":null,"url":null,"abstract":"Objective: To compare the effect of L-asparaginase and pegaspargase in the treatment of adult acute lymphoblastic leukemia. Methods: In this study, 96 patients who received treatment at the Shaanxi Provincial People’s Hospital from April 2019 to April 2021 were selected. The control group received L-asparaginase treatment, and the observation group received pegaspargase treatment. The curative effect and adverse reaction rate were compared between the two groups. Results: Comparing the experimental statistical results of the observation and the control groups, it can be concluded that the effect of the former group is better than that of the latter group in terms of clinical curative effect and statistics of adverse reactions. Conclusion: In the treatment of adult acute lymphoblastic leukemia, the application of pegaspargase therapy has a significantly better clinical effect and is worthy of further promotion.","PeriodicalId":20511,"journal":{"name":"Proceedings of Anticancer Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of the Effects of L-asparaginase and Pegaspargase in the Treatment of Adult Acute Lymphoblastic Leukemia\",\"authors\":\"Limin Hou, Lan Li\",\"doi\":\"10.26689/par.v7i5.5157\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To compare the effect of L-asparaginase and pegaspargase in the treatment of adult acute lymphoblastic leukemia. Methods: In this study, 96 patients who received treatment at the Shaanxi Provincial People’s Hospital from April 2019 to April 2021 were selected. The control group received L-asparaginase treatment, and the observation group received pegaspargase treatment. The curative effect and adverse reaction rate were compared between the two groups. Results: Comparing the experimental statistical results of the observation and the control groups, it can be concluded that the effect of the former group is better than that of the latter group in terms of clinical curative effect and statistics of adverse reactions. Conclusion: In the treatment of adult acute lymphoblastic leukemia, the application of pegaspargase therapy has a significantly better clinical effect and is worthy of further promotion.\",\"PeriodicalId\":20511,\"journal\":{\"name\":\"Proceedings of Anticancer Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of Anticancer Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26689/par.v7i5.5157\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of Anticancer Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26689/par.v7i5.5157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of the Effects of L-asparaginase and Pegaspargase in the Treatment of Adult Acute Lymphoblastic Leukemia
Objective: To compare the effect of L-asparaginase and pegaspargase in the treatment of adult acute lymphoblastic leukemia. Methods: In this study, 96 patients who received treatment at the Shaanxi Provincial People’s Hospital from April 2019 to April 2021 were selected. The control group received L-asparaginase treatment, and the observation group received pegaspargase treatment. The curative effect and adverse reaction rate were compared between the two groups. Results: Comparing the experimental statistical results of the observation and the control groups, it can be concluded that the effect of the former group is better than that of the latter group in terms of clinical curative effect and statistics of adverse reactions. Conclusion: In the treatment of adult acute lymphoblastic leukemia, the application of pegaspargase therapy has a significantly better clinical effect and is worthy of further promotion.
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