总状芦笋水乙醇提取物对丙烯酰胺诱导斑马鱼神经行为模式的影响

IF 0.2 Q4 Biochemistry, Genetics and Molecular Biology
Anubhav Dubey, Niladry S. Ghosh, Ranjit Singh
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引用次数: 0

摘要

神经心理学评估是一种评估一个人的大脑功能的测试。识字、语言使用、注意力、学习、处理速度、推理、记忆、解决问题、个性和其他才能都被评估。本研究旨在探讨总状芦笋种子水提液和乙醇提液对丙烯酰胺诱导实验斑马鱼神经行为模式的影响。在新槽试验中,总状芦笋种子提取物组的顶入次数、顶停留时间、顶入潜伏期和总行进距离均大于丙烯酰胺组,而底入次数和底停留时间均小于丙烯酰胺组。在明暗测试中,II组斑马鱼用0.75 mM丙烯酰胺处理后,在光区待的时间减少,表现出焦虑。在我们的研究中,用不同浓度的总状芦笋种子提取物和乙醇提取物对斑马鱼进行预处理,效果显著。在大田试验中,与丙烯酰胺对照组相比,不同剂量的总状芦笋种子提取物显著提高了外区(s)和内区(s)时间。在y型迷宫实验中,与丙烯酰胺对照组相比,不同剂量的总状芦笋种子提取物在进入新臂的数量和迷宫中行走的总距离方面表现出剂量影响的显著改善。与丙烯酰胺对照相比,不同剂量的总状芦笋种子提取物在新手臂上花费的时间显着增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of aqueous and ethanolic seed extract of Asparagus racemosus Linn on neurobehavioral pattern of acrylamide induced experimental Zebra fish
A neuropsychological assessment is a test that assesses how well a person's brain functions. Literacy, language use, attention, learning, processing speed, reasoning, memory, problem-solving, personality and other talents are all assessed. The purpose of this study is to assess the effects of aqueous and ethanolic seed extracts of Asparagus racemosus Linn on the neurobehavioral pattern of acrylamide-induced experimental Zebra fish. In the novel tank test, the number of top entries, top remain time, top entry latency and total distance traveled were all greater in the Asparagus racemosus Linn seed extract group than in the acrylamide group, while the number of bottom entries and bottom duration of stay were lower. In the light-dark test, group II Zebrafish treated with 0.75 mM acrylamide showed anxiety by spending less time in the light zone. In our study, Zebrafish pre-treated with aqueous and ethanolic seed extracts of different concentrations of Asparagus racemosus Linn significantly reversed. In the open field test, the Asparagus racemosus Linn seed extract at different doses significantly improved outer zone (s) and inner zone (S) times compared to the acrylamide control group. In the Y-maze test, the Asparagus racemosus Linn seed extract at different dosages exhibited a dose-influenced significant improvement in the number of entry points to new arms and the total distance walked in the maze in comparison to the acrylamide control group. When compared to the acrylamide control, the Asparagus racemosus Linn seeds extract at various doses demonstrated a significant rise in the amount of time spent in the new arm.
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来源期刊
Research Journal of Biotechnology
Research Journal of Biotechnology 工程技术-生物工程与应用微生物
CiteScore
0.60
自引率
0.00%
发文量
192
审稿时长
1.5 months
期刊介绍: We invite you to contribute Research Papers / Short Communications / Review Papers: -In any field of Biotechnology, Biochemistry, Microbiology and Industrial Microbiology, Soil Technology, Agriculture Biotechnology. -in any field related to Food Biotechnology, Nutrition Biotechnology, Genetic Engineering and Commercial Biotechnology. -in any field of Biotechnology related to Drugs and Pharmaceutical products for human beings, animals and plants. -in any field related to Environmental Biotechnolgy, Waste Treatment of Liquids, Soilds and Gases; Sustainability. -in inter-realted field of Chemical Sciences, Biological Sciences, Environmental Sciences and Life Sciences. -in any field related to Biotechnological Engineering, Industrial Biotechnology and Instrumentation. -in any field related to Nano-technology. -in any field related to Plant Biotechnology.
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