良性移行脑膜瘤1级肿瘤1例及文献复习

Sunil V Jagtap, Loknath Srimanto Sarkar, Shubham S Jagtap
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摘要

移行性脑膜瘤是一种少见的良性脑膜瘤。移行性脑膜瘤是WHO一级脑膜瘤,其特征是脑膜上皮细胞和纤维结构模式共存。女,35岁,间歇性发热,头痛1个月。在过去的两天里,意识水平发生了变化,还出现了呕吐。脑MRI采用TI加权自旋回波2加权涡轮自旋回波和涡轮流体衰减反转恢复:FLAIR扩散序列。在右侧额颞区,沿蝶骨右侧大翼,可见一个大的分叶状强化病灶,提示脑膜瘤。手术切除肿瘤。组织病理学显示为良性肿瘤,由脑膜上皮和纤维增生组成。脑膜上皮细胞呈束状排列,成纤维细胞肿瘤呈合胞型。细胞核圆形,均匀,无核仁。染色质细而开放。肿瘤细胞呈梭形,胞质丰富,呈粉红色,细胞膜模糊,细胞核无明显特征。无有丝分裂象和异型性,可见散在砂粒体。组织病理学诊断为良性WHO 1级肿瘤-移行性脑膜瘤。由于影像和组织病理学技术的增强和改进,脑膜瘤的发病率增加,这将有助于患者更好的预后。我们在此报告一例WHO一级移行性脑膜瘤良性肿瘤的临床、放射影像和组织病理学结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transitional meningioma benign who grade 1 tumor-A case and review of the literature
Transitional meningioma (TM) is an uncommon benign meningioma. Transitional meningioma is a WHO grade I meningioma characterized by the coexistence of meningothelial cells and fibrous architectural patterns. A35 year female presented with history of intermittent fever, headache of 1 month duration. And since last 2 days with altered level of consciousness and vomiting. : MRI of the brain was performed using TI weighted spin echoI2 weighted turbo spin echo and turbo Fluid-attenuated inversion recovery: FLAIR diffusion sequences. It showed a large, lobulated, enhancing lesion in right fronto-temporal region, along right greater wing of sphenoid suggestive of meningioma. Surgical excision of tumor was done. On histopathology showed a benign tumor consists of meningothelial and fibrous proliferation. The meningothelial cells were arranged in fascicles, with the fibroblastic tumor in syncytial pattern. The nuclei were round, uniform without nucleoli. The chromatin was fine and open. The tumor cells were spindle having abundant pink cytoplasm, indistinguishable cell membranes and bland nuclear features. Mitotic figures and atypia were absent .Scattered Psammoma bodies were noted. Histopathological diagnosis was gives as benign WHO grade 1 tumor- transitional meningioma. Due to enhanced and improved imaging, histopathological techniques the increased incidence of meningiomas is observed and it will be helpful for better outcomes of patients. We are presenting this case of transitional meningioma benign tumor WHO grade1for its clinical, radioimaging and histopatholgical findings.
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