桥小脑角肿瘤的回顾性研究:一项单一的机构研究

IF 0.6 Q3 Medicine
Shashivadhanan Sundaravadhanan, B S Faraz Ahmed, Neerav Porwal, Manish Sharma, Mannu Tiwari
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引用次数: 0

摘要

脑桥小脑角肿瘤是一种罕见的颅内肿瘤,多发于小脑与脑桥之间。由于其复杂的解剖结构和靠近关键的神经血管结构,这些肿瘤的治疗可能具有挑战性。手术干预往往是必要的,以达到良好的结果。本回顾性研究的主要目的是分析桥小脑角肿瘤的临床和影像学特征,确定病理类型,评估手术可切除性,并评估术后预后。该研究招募了14名在浦那武装部队医学院接受桥小脑角肿瘤手术治疗的患者。回顾性分析,考虑人口统计资料,临床表现,影像学特征和手术结果。前庭神经鞘瘤是主要的肿瘤类型,大多数肿瘤出现在30岁至50岁之间。临床表现为SNHL、小脑功能障碍、头痛、感觉三叉神经功能障碍。相当大比例(86%)的患者术前没有有用的听力。手术结果显示不同程度的成功,在一小部分病例中实现了完全切除。值得注意的是,在相当大比例的患者中完成了面神经的解剖保存。术后评估,使用House Brackmann系统,显示正面的面神经功能结果在相当大的百分比。并发症包括脑脊液漏(14%)、脑膜炎(7%)和下颅神经麻痹(7%)。综上所述,手术干预在桥脑小脑肿瘤的治疗中起着至关重要的作用。手术入路的选择应根据肿瘤特点和患者因素进行个体化选择,以最大限度地切除肿瘤和减少并发症为目标。需要进一步的研究和手术技术的进步来优化桥脑小脑肿瘤患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A retrospective study of cerebellopontine angle tumours: A single instituitional study
: Cerebellopontine angle (CPA) tumors are rare intracranial neoplasms that arise in the region between the cerebellum and the pons. These tumors can be challenging to treat due to their complex anatomy and proximity to critical neurovascular structures. Surgical intervention is often necessary to achieve a favorable outcome. The primary objectives of this retrospective study are to analyze the clinical and radiological characteristics of cerebellopontine angle tumors, identify pathological types, assess surgical resectability, and evaluate postoperative outcomes. : The study enrolled 14 patients who underwent surgical intervention for cerebellopontine angle tumors at Armed forces medical college, Pune. A retrospective analysis was performed, considering demographic data, clinical presentations, imaging characteristics and surgical outcomes. : Vestibular schwannoma was the predominant tumor type with majority of tumors manifesting between third to fifth decades. Clinical manifestation included SNHL, cerebellar dysfunction, headache and sensory trigeminal dysfunction. A substantial proportion (86%) presented with no useful hearing preoperatively. Surgical outcomes indicated varying degrees of success, with total resection achieved in a subset of cases. Notably, anatomical preservation of the facial nerve was accomplished in a significant proportion of patients. Postoperative assessments, using the House Brackmann system, revealed positive facial nerve function outcomes in a substantial percentage. Complications included cerebrospinal fluid leak (14%), meningitis(7%) and lower cranial nerve paresis (7%). : In conclusion, surgical intervention plays a crucial role in the management of cerebellopontine tumors. The choice of surgical approach should be individualized based on tumor characteristics and patient factors, with the goal of achieving maximum tumor resection while minimizing complications. Further research and advancements in surgical techniques are needed to optimize outcomes for patients with cerebellopontine tumors.
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来源期刊
CiteScore
0.90
自引率
0.00%
发文量
226
审稿时长
3 months
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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