{"title":"致死性鬼臼碱中毒合并多器官毒性1例","authors":"BhaktiU Sarangi, Shridhar Jadhav, Ajay Walimbe, Manikiran Reddy, Siddhi Gawhale, RHema Priya","doi":"10.4103/jpcc.jpcc_47_23","DOIUrl":null,"url":null,"abstract":"Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its toxicity includes life-threatening neurological and multisystem complications. We report a case of a 2-year-old girl with accidental podophyllin poisoning causing multi-organ dysfunction who did not survive despite timely aggressive support and explore the possibility of early use of activated charcoal and role of extra-corporeal therapies such as hemoperfusion as a life-saving measure in such situations.","PeriodicalId":34184,"journal":{"name":"Journal of Pediatric Critical Care","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fatal podophyllin poisoning with multi-organ toxicity: A case report\",\"authors\":\"BhaktiU Sarangi, Shridhar Jadhav, Ajay Walimbe, Manikiran Reddy, Siddhi Gawhale, RHema Priya\",\"doi\":\"10.4103/jpcc.jpcc_47_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its toxicity includes life-threatening neurological and multisystem complications. We report a case of a 2-year-old girl with accidental podophyllin poisoning causing multi-organ dysfunction who did not survive despite timely aggressive support and explore the possibility of early use of activated charcoal and role of extra-corporeal therapies such as hemoperfusion as a life-saving measure in such situations.\",\"PeriodicalId\":34184,\"journal\":{\"name\":\"Journal of Pediatric Critical Care\",\"volume\":\"34 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pediatric Critical Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jpcc.jpcc_47_23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pediatric Critical Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jpcc.jpcc_47_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fatal podophyllin poisoning with multi-organ toxicity: A case report
Accidental poisoning with household products is one of the leading causes of involuntary injuries among children in low- and middle-income countries. Podophyllin poisoning is a rare and potentially fatal occurrence. The podophyllotoxin is a lipid-soluble cytotoxic compound with no antidote and its toxicity includes life-threatening neurological and multisystem complications. We report a case of a 2-year-old girl with accidental podophyllin poisoning causing multi-organ dysfunction who did not survive despite timely aggressive support and explore the possibility of early use of activated charcoal and role of extra-corporeal therapies such as hemoperfusion as a life-saving measure in such situations.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
