三级保健中心儿童百草枯中毒的临床流行病学概况:病例系列

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引用次数: 0

摘要

目的和目的:本病例系列是为了了解儿童百草枯中毒的临床-流行病学概况,以及由于没有标准治疗指南,现有治疗指南对改善儿科人群预后的影响。材料与方法:在2021年10月至2023年2月的研究期间,选取9名儿童,收集人口统计学资料,评估临床参数,如出现时间、症状和接受的急救,LFT、RFT等实验室参数,获得胸片并监测序列值。根据现有的治疗建议,免疫抑制治疗和血液透析是在个案的基础上开始的。结果:9例患儿中,女性6例(67%),平均年龄15 ~ 18岁。9例患儿中有8例(89%)发生急性肾功能衰竭。7名儿童接受了血液透析。5名(55%)儿童出现肝功能障碍。9例患儿中3例(67%)存活。结论:本研究表明,如果患儿在摄入该化合物8小时内就诊,摄入量小于20ml, 8小时内早期开始血液透析,并进行免疫抑制治疗,可降低死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinico-epidemiological Profile of Paraquat Poisoning in Children at a Tertiary Care Centre: Case Series
Aims and objectives: This case series is done to know the Clinico-epidemiological profile of paraquat poisoningin children and also the implication of available treatment guidelines in improving outcomes in the paediatricpopulation as there are no standard treatment guidelines available.Materials and Methods: Nine children were selected during the study period of October 2021 to February 2023,demographic data were collected, clinical parameters were assessed with details such as time of presentation,symptoms and first aid received, laboratory parameters such as LFT, RFT, chest radiographs obtained and serialvalues monitored. Treatment as per the available recommendation was initiated with immunosuppressive therapyand haemodialysis on a case-to-case basis.Results: Among the 9 children, there were 6 females (67%) with an average age group of 15–18 years. eight (89%)of the 9 children developed acute renal failure. Seven children underwent haemodialysis. Five (55%) childrendeveloped hepatic dysfunction. Among the 9 children, 3 (67%) survived.Conclusion: The study reveals that the mortality rate can be reduced, if the child presented to the hospital within8 hours of ingestion of the compound, amount ingested is less than 20 ml, and early initiation of Haemodialysiswithin 8 hours and a trail of immunosuppressive therapy.
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