Study of Stroke Due to Intra Cranial Atherosclerosis in Bihar Population

Background: Ischemic stroke is quite heterogeneous in its patho-physiological mechanism associated withatherosclerosis. Little is known about measures for prevention of the disease apart from latest technologies andmedications.Method: 100 patients of different age groups were studied with MRA, to rule out occlusion or lesion; tropicaldistribution of infarction, clinical manifestations, recurrence after treatment was also noted.Results: Clinical manifestations included 33% alcoholic, 21% homocystine, 80% HTN, 54% DM, 30% Hyperlipidemia,35% smoking, 48% HTN + DM, 17% HTN + DM +Hyper-lipidemia, 7% HTN + DM + Hyper-lipidemia,+ smoking + Alcohol. Highest occlusion was observed 51 (39.9%) in MCA followed by 20 (14.4%) ICA, 23 (16.6%)BA, 18 (13.04%) VA and least was 2 (1.4%) in VA+BA. Highest tropical distribution of infarction was 28% corticalfollowed by 24% sub cortical and cortical, 23% cortical, 11% cerebellum, 8% Brainstem and recurrence wasobserved in 19% patients.Conclusion: The present pragmatic study will help for efficient management and risk control for Neuro-physicianand neurosurgeon because risk factor control remains the best strategy for preventing recurrence becauserecurrence of the stroke worsen the physical and mental conditions of the patients