特应性皮炎表皮功能障碍的现代治疗选择

Q4 Medicine

Voprosy Sovremennoi Pediatrii - Current Pediatrics Pub Date : 2023-11-05 DOI:10.15690/vsp.v22i5.2619

Eduard T. Ambarchyan, Anastasiya D. Kuzminova, Vladislav V. Ivanchikov

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引用次数: 0

摘要

特应性皮炎(AD)是一种慢性炎症性皮肤病。其发病机制的关键组成部分是表皮屏障功能障碍。聚丝蛋白和相关的聚丝蛋白基因突变在这一问题中起着关键作用。如今，新的局部产品(润肤剂)已经被创造出来并付诸实践，目的是为AD患者提供更个性化的治疗方法，提高治疗效果。这些药物将使我们能够恢复表皮屏障功能，实现疾病症状的消除。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modern Treatment Options for Epidermal Dysfunction at Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease. Its crucial component of pathogenesis is malfunction of the epidermal barrier. Filaggrin protein and associated mutations in the filaggrin gene play one of the key roles in this problem. Nowadays new topical products (emollients) has been created and implemented into practice with the aim of more personalized approach and increased therapy efficacy in patients with AD. Such drugs would allow us to restore epidermal barrier function and to achieve elimination of disease symptoms.

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来源期刊

Voprosy Sovremennoi Pediatrii - Current Pediatrics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.70

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The main purpose of the academic journal "Current Pediatrics" is to cover the issues related to health, emotional state, and social adaptation of children. In the journal we publish the most pressing issues of research and applied problems (such as social paediatrics; clinical findings, anamnesis, and diagnosis of paediatric diseases; prevention and rehabilitation; supply of healthy and sick child), reviews on the current state of medical science and management of health care in Russia. Along with the concern for providing a high level of basic research publications, the journal, being a mass media tool, tends to meet the interests and requirements of practitioners from different regions and bring up vital and urgent questions. To accomplish this purpose the journal includes the materials of practical interest presented in the following sections: "Exchange of experience", "Doctor''s aid", "Continuous professional education", "Expert Opinion". The journal presents actual official information from the Union of Paediatricians of Russia and publishes materials on the history of medical science, congresses, seminars, conferences, both in our country and abroad.