None Muhsn Ali hazam,, None Raheem Jameel Mahesein, None H. N. K. AL-Salman
{"title":"氟西地酸和氧化锌吡唑啉衍生物的抗菌和抗氧化活性研究","authors":"None Muhsn Ali hazam,, None Raheem Jameel Mahesein, None H. N. K. AL-Salman","doi":"10.36329/jkcm/2023/v2.i10.13888","DOIUrl":null,"url":null,"abstract":"pyrazoline was synthesized as a derivative, then the polymerization of pyrazoline was carried out with fusidic acid and zinc oxide. All the physical properties affecting the construction process, such as Thin-layer chromatography, solubility, the effect of buffer solutions, and temperatures, were studied. Physical diagnostics such as DSC, TGA, and FT-IR were also investigated. The study of the biological activity of the polymer resulting from the interaction of pyrimidine with fusidic acid and zinc oxide, where the study was conducted against three types of bacteria, and the results of the study were compared with the activity of fusidic acid alone once and with zinc oxide alone again as a control. The results showed that the process of polymerization of pyrazoline with fusidic acid and zinc oxide gives more excellent results against bacteria compared to fusidic acid alone and zinc oxide alone.","PeriodicalId":489104,"journal":{"name":"Journal of Kufa for Chemical Sciences","volume":"119 3","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study of the biological activity of pyrazoline derivatives with fusidic acid and ZnO as an antibacterial and antioxidant\",\"authors\":\"None Muhsn Ali hazam,, None Raheem Jameel Mahesein, None H. N. K. AL-Salman\",\"doi\":\"10.36329/jkcm/2023/v2.i10.13888\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"pyrazoline was synthesized as a derivative, then the polymerization of pyrazoline was carried out with fusidic acid and zinc oxide. All the physical properties affecting the construction process, such as Thin-layer chromatography, solubility, the effect of buffer solutions, and temperatures, were studied. Physical diagnostics such as DSC, TGA, and FT-IR were also investigated. The study of the biological activity of the polymer resulting from the interaction of pyrimidine with fusidic acid and zinc oxide, where the study was conducted against three types of bacteria, and the results of the study were compared with the activity of fusidic acid alone once and with zinc oxide alone again as a control. The results showed that the process of polymerization of pyrazoline with fusidic acid and zinc oxide gives more excellent results against bacteria compared to fusidic acid alone and zinc oxide alone.\",\"PeriodicalId\":489104,\"journal\":{\"name\":\"Journal of Kufa for Chemical Sciences\",\"volume\":\"119 3\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Kufa for Chemical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36329/jkcm/2023/v2.i10.13888\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Kufa for Chemical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36329/jkcm/2023/v2.i10.13888","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Study of the biological activity of pyrazoline derivatives with fusidic acid and ZnO as an antibacterial and antioxidant
pyrazoline was synthesized as a derivative, then the polymerization of pyrazoline was carried out with fusidic acid and zinc oxide. All the physical properties affecting the construction process, such as Thin-layer chromatography, solubility, the effect of buffer solutions, and temperatures, were studied. Physical diagnostics such as DSC, TGA, and FT-IR were also investigated. The study of the biological activity of the polymer resulting from the interaction of pyrimidine with fusidic acid and zinc oxide, where the study was conducted against three types of bacteria, and the results of the study were compared with the activity of fusidic acid alone once and with zinc oxide alone again as a control. The results showed that the process of polymerization of pyrazoline with fusidic acid and zinc oxide gives more excellent results against bacteria compared to fusidic acid alone and zinc oxide alone.