{"title":"血清尿酸(SUA)水平和SUA/血清肌酐(Scr)比值是糖尿病患者微量白蛋白尿的预测性生物标志物吗?","authors":"Mercan TAŞTEMUR, Çağla ÖZDEMİR","doi":"10.7197/cmj.1346682","DOIUrl":null,"url":null,"abstract":"Background: The pathogenesis of diabetic nephropathy (DN) is very complex and is still not well understood. SUA has been associated with metabolic risk in a wide range of diseases. In this study, we aimed to investigate the effect of SUA and SUA/Scr ratio on renal function using glomerular filtration rate (GFR) and microalbuminuria.
 Methods: A total of 399 patients with diabetes alone, excluding other conditions that affect uric acid levels, were included in the study. Patients were divided into normoalbuminuria (n:247) and microalbuminuria (n:152) groups. SUA, SUA/Scr ratios were compared.
 Results: Female gender was 53.4% in the normoalbuminuria group and 57.9% in the microalbuminuria group. There was no significant difference in gender between the groups. In the microalbuminuria group, SUA (p=0.032), glucose (p","PeriodicalId":10750,"journal":{"name":"Cumhuriyet medical journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Is the serum uric acid (SUA) level and SUA/serum creatinine (Scr) ratio a predictive biomarker for microalbuminuria in patients with diabetes mellitus?\",\"authors\":\"Mercan TAŞTEMUR, Çağla ÖZDEMİR\",\"doi\":\"10.7197/cmj.1346682\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The pathogenesis of diabetic nephropathy (DN) is very complex and is still not well understood. SUA has been associated with metabolic risk in a wide range of diseases. In this study, we aimed to investigate the effect of SUA and SUA/Scr ratio on renal function using glomerular filtration rate (GFR) and microalbuminuria.
 Methods: A total of 399 patients with diabetes alone, excluding other conditions that affect uric acid levels, were included in the study. Patients were divided into normoalbuminuria (n:247) and microalbuminuria (n:152) groups. SUA, SUA/Scr ratios were compared.
 Results: Female gender was 53.4% in the normoalbuminuria group and 57.9% in the microalbuminuria group. There was no significant difference in gender between the groups. In the microalbuminuria group, SUA (p=0.032), glucose (p\",\"PeriodicalId\":10750,\"journal\":{\"name\":\"Cumhuriyet medical journal\",\"volume\":\"5 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cumhuriyet medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7197/cmj.1346682\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cumhuriyet medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7197/cmj.1346682","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Is the serum uric acid (SUA) level and SUA/serum creatinine (Scr) ratio a predictive biomarker for microalbuminuria in patients with diabetes mellitus?
Background: The pathogenesis of diabetic nephropathy (DN) is very complex and is still not well understood. SUA has been associated with metabolic risk in a wide range of diseases. In this study, we aimed to investigate the effect of SUA and SUA/Scr ratio on renal function using glomerular filtration rate (GFR) and microalbuminuria.
Methods: A total of 399 patients with diabetes alone, excluding other conditions that affect uric acid levels, were included in the study. Patients were divided into normoalbuminuria (n:247) and microalbuminuria (n:152) groups. SUA, SUA/Scr ratios were compared.
Results: Female gender was 53.4% in the normoalbuminuria group and 57.9% in the microalbuminuria group. There was no significant difference in gender between the groups. In the microalbuminuria group, SUA (p=0.032), glucose (p
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