CLINICAL AND LABORATORY INDICATORS OF PREGNANT COWS PRONE TO THE DEVELOPMENT OF GESTOSIS

The article presents materials on studying clinical and laboratory indicators of pregnant cows at 60 days of gestation, prone to the development of gestosis. In cows with the uterine fetal growth retardation syndrome at 2 months of pregnancy, subsequently complicated by gestosis, the established morphobiochemical changes indicate failures in the protein metabolism, functioning of the liver, kidneys, and the circulatory system. The changes also show an intensive accumulation of lipid peroxidation products, with a decrease in the activity of the enzymatic and non-enzymatic link of the AOD. The development of the fetal intrauterine growth retardation syndrome occurs against the background of a trophism disorders in the developing embryo. This at early stages of pregnancy is clinically manifested by a decrease in the size of the uterine horn cavity by 22.2-34.2%, the length of the fetus – by 41.5-48.9%, the body diameter – by 19.9-28.9%, the size of the corpus luteum of the ovary – by 15.7-24.1%.