#35209三级护理医院icu的医院感染发生率和抗生素谱

Sami Ur Rehman
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摘要

请确认是否已申请或批准伦理委员会的批准:不相关(见本页底部的信息)背景和目的抗菌素耐药性(AMR)已成为一个全球性问题。不仅减少了治疗选择,而且与抗生素的滥用和过度使用有关,对低收入国家构成严重威胁。本研究确定了拉合尔医生医院和医疗中心外科icu (SICU)住院患者的抗生素谱。方法本研究为回顾性横断面研究。在我们的研究期间,共有502例患者入住ICU。记录364例患者的血液、气管和尿液培养报告。所有培养物均按照CLSI定义的标准微生物学方案进行处理。cle用于尿液培养,而Mac-Conkey, chocolate和Blood Agar用于气管和痰培养。血培养在BACT/ALERT自动血培养系统上进行。采用SPSS 64位版进行统计分析。结果本组364例患者中,不同部位培养物分别为血液(54%)、尿液(33%)和气管(13%)。在血液培养中,没有分离出任何有机体。在气管培养中,最常见的细菌是克雷伯菌(5),其次是不动杆菌(4)和假单胞菌(3)。在尿液培养中,最常见的细菌是大肠杆菌(4),其次是克雷伯菌(3)和假单胞菌(2)。万古霉素和利奈唑胺对葡萄球菌的耐药性为0%,粘菌素对不动杆菌和克雷伯菌的耐药性为0%。莫西沙星对大肠杆菌耐药。结论革兰氏阴性菌是ICU感染的主要原因。革兰氏阴性菌(88.46%)多于革兰氏阳性菌(11.53%)。我们需要更明智地开出广谱抗生素,以减轻对敏感菌株的压力。附件抗生素图dhmc.docx
本文章由计算机程序翻译,如有差异,请以英文原文为准。
#35209 Incidence of nosocomial infections in icu of a tertiary care hospital and antibiogram

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)

Background and Aims

Antimicrobial resistance (AMR) has become a global issue. Not only decreasing the treatment options but serious threat to low-income countries associated with both misuse and overuse of antibiotics. This study has determined the antibiogram profile of patients admitted in SURGICAL icu (SICU) at Doctors Hospital and Medical Centre, Lahore.

Methods

This study was retrospective cross-sectional in nature.Total 502 patients were admitted in ICU during our study period.Blood, tracheal and urine culture reports of 364 patients were recorded for the purpose of study.All cultures were processed in accordance with standard microbiological protocols defined by CLSI. CLED used for urine cultures, while Mac-Conkey, Choclate and Blood Agar were being used for tracheal and sputum cultures. Blood cultures were processed on BACT/ALERT automated blood culture system.Statistical analysis were performed using the SPSS 64-bit version.

Results

Among 364 patients analyzed in the study, the cultures obtained from different sites were Blood (54%), Urine (33%) and tracheal (13%). Among blood cultures, no organism was isolated.Among tracheal cultures, most common organisms isolated were Klebsiella (5), followed by Acinetobacter (4) and Pseudomonas (3).Among urine cultures, most common organism isolated was E. coli (4), then Klebsiella (3) and Pseudomonas (2).Vancomycin and Linezolid showed zero percent resistance to Staphylococcus sp. Collistin showed zero percent resistance for Acinetobacter and Klebsiella. Moxifloxacin was resistant for E. coli.

Conclusions

The gram-negative bacteria were the major cause of infection in the ICU. Gram negative organisms(88.46%) were detected more than gram positive organisms(11.53%). We need to prescribe broad-spectrum antibiotics more wisely to reduce pressure on sensitive strains.

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antibiogram dhmc.docx
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