稳定型慢性阻塞性肺疾病的心脏异常:相关性和预测因素

IF 0.2 Q4 RESPIRATORY SYSTEM
Hend Ismael, Abdellah Hamed, Shimaa Nour
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引用次数: 0

摘要

背景稳定期慢性阻塞性肺疾病(COPD)患者更容易发生心脏异常,这增加了发病率和死亡率。本研究的目的是探讨稳定期COPD患者这些异常的相关性和可能的预测因素。患者和方法我们进行了一项前瞻性队列研究,包括91例稳定的COPD病例,他们在2021年8月至2022年1月期间被一家三级卫生保健中心收治。对所有参与者进行肺活量测定、动脉血气和心电图检查。根据GOLD指南(2021)对其进行分类,并根据美国和欧洲超声心动图协会ASE的建议通过二维多普勒超声心动图进行评估。结果纳入COPD患者91例;平均年龄60.5岁,男性居多(62.6%)。患者中76.9%为吸烟者,49.5%为II型呼吸衰竭。最常见的心电图异常表现为肺动脉P、心室异位和缺血性改变,在重度COPD患者中更为常见(94.29%)。超声心动图评估显示近65%的患者有异常表现,重症组更多。最常见的表现是肺动脉高压(PH)(72.5%)、右心室扩张(49.5%)和运动障碍(21.98%)。心脏异常的危险因素是呼吸衰竭、COPD病程、合并症和COPD分期。结论右心室扩张、运动不足、PH值与超声心动图表现及COPD严重程度呈正相关。呼吸衰竭和COPD病程是心律失常的独立预测因素;COPD分期和合并症数量是心脏缺血的预测因子,而呼吸衰竭和合并症是PH的预测因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiac abnormalities in stable chronic obstructive pulmonary disease: correlations and predictors
Abstract Background Patients with stable chronic obstructive pulmonary disease (COPD) are more likely to have cardiac abnormalities, which increase morbidity and mortality. The aim of the study is to explore correlations and probable predictors for these abnormalities in stable COPD patients. Patients and methods We conducted a prospective cohort study including 91 stable COPD cases, who were admitted to a tertiary health-care center during the period from August 2021 to January 2022. Spirometry, arterial blood gas, and ECG were performed for all participants. They were categorized using GOLD guidelines (2021) and assessed by two-dimensional Doppler echocardiography using the American and European Association of Echocardiography ASE recommendations. Results The study included 91 COPD patients; their mean age was 60.5 years with male predominance (62.6%). Of the patients, 76.9% were smokers and 49.5% of patients have respiratory failure type II. The most common abnormal ECG findings were P pulmonale, ventricular ectopic, and ischemic changes, which were more detected in severe COPD patients (94.29%). Echocardiographic assessment showed abnormal findings in almost 65%, more in the severe group. The most frequent findings were signs of pulmonary hypertension (PH) (72.5%), right ventricular dilatation (49.5%), and hypokinesia (21.98%). Risk factors of cardiac abnormalities were respiratory failure, COPD duration, comorbidities, and COPD stage. Conclusion Right ventricle dilatation, hypokinesia, and PH showed a positive correlation with echocardiographic findings and COPD severity. Respiratory failure and COPD duration were independent predictors of arrhythmia; COPD stage and the number of comorbidities were predictors of cardiac ischemia, while respiratory failure and comorbidities were predictors of PH.
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来源期刊
自引率
0.00%
发文量
46
审稿时长
22 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of The Egyptian Journal of Chest Diseases and Tuberculosis aims to publish and inform readers and all chest physicians of the progress in medical research concerning all aspect of chest diseases. Publications include original articles review articles, editorials, case studies and reports which are relevant to chest diseases. The Journal also aims to highlight recent updates in chest medicine. . Articles with clinical interest and implications will be given preference.
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