问题4

IF 0.2 Q4 PEDIATRICS
N Geddara, L Mubaiwa, R Thejpal, C Hendricks
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引用次数: 0

摘要

背景。癌症儿童营养不良是一个普遍问题,特别是在发展中国家。入院时和治疗期间确定营养状况对降低发病率和死亡率至关重要。目标。本研究报告了癌症儿童营养不良的发生率及其对预后的影响。方法。一项回顾性研究确定了2017年1月至2018年6月在南非学术医院英科西阿尔伯特卢图利中心医院(IALCH)新诊断的癌症儿童。该队列包括139名患者。人口统计学、人体测量学和结果数据从医院电子数据库中收集。采用世界卫生组织(世卫组织)的标准对营养状况进行分类。评估了第一年营养状况对死亡率、住院时间和感染状况的影响。结果。139例患者中营养不良发生率为31.7%(17.3%消瘦,7.2%发育不良,7.2%消瘦并发育不良)。患有实体瘤的儿童消瘦的发生率高于患有血液系统恶性肿瘤的儿童,尽管这没有统计学意义(分别为21.2% vs . 7.7%, p值0.242)。与营养良好的患者相比,营养不良患者的早期死亡率、住院时间或感染率没有显著差异。结论。在我们的癌症患者队列中,营养不良的发生率很高,但与死亡率、住院时间或感染风险的增加无关。建议使用基于手臂和体重/身高的人体测量相结合的更大样本量来证实这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Issue 4
Background. Malnutrition in children with cancer is a common problem, especially in developing countries. Determination of nutritional status on admission and during treatment is crucial to reduce morbidity and mortality. Objectives. This study reports the prevalence of malnutrition in children with cancer and its impact on outcomes. Methods. A retrospective study identified newly diagnosed children with cancer between January 2017 and June 2018 at Inkosi Albert Luthuli Central Hospital (IALCH), an academic hospital in South Africa (SA). The cohort comprised 139 patients. Demographic, anthropometric and outcome data were collected from the hospital electronic database. World Health Organization (WHO) criteria were applied to classify nutritional status. The impact of nutritional status on mortality, length of hospital stay and infection status in the first year was assessed. Results. The prevalence of malnutrition in our cohort of 139 patients was 31.7% (17.3% wasted, 7.2% stunted and 7.2% wasted and stunted). There was a higher incidence of wasting in children with solid tumours than those with haematological malignancies although this was not statistically significant (21.2% v. 7.7% respectively, p-value 0.242). No significant difference in early mortality, length of hospital stay or rate of infection was noted in malnourished patients compared with well-nourished patients. Conclusion. The prevalence of malnutrition in our cohort with cancer was high but not associated with an increased risk of mortality, hospital stay or infection. A larger sample size using a combination of arm- and weight/height-based anthropometry is recommended to confirm these findings.
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
21
审稿时长
12 weeks
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